Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862807 | 0.88 | ELANE (0.47) | MPLELANEKMT2AMEN1MAPT | |
| SCHEMBL7857421 | 0.87 | ELANE (0.46) | MPLELANEKMT2AMEN1MAPT | |
| SCHEMBL5674095 | 0.85 | ELANE (0.47) | MPLELANEKMT2AMEN1MAPT | |
| SCHEMBL7865647 | 0.83 | ELANE (0.46) | MPLELANEKMT2AMEN1MAPT | |
| SCHEMBL27324940 | 0.82 | ELANE (0.44) | MPLELANEKMT2AMEN1MAPT | |
| SCHEMBL2761135 | 0.81 | ELANE (0.47) | MPLELANEKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL27323561 | 0.81 | ELANE (0.43) | MPLELANEKMT2AMEN1MAPT | |
| SCHEMBL6155652 | 0.80 | PGAM1 (0.44) | MPLKMT2AMEN1MAPTHPGD | |
| SCHEMBL29700277 | 0.80 | PGAM1 (0.44) | MPLKMT2AMEN1MAPTHPGD | |
| SCHEMBL3885120 | 0.78 | ELANE (0.47) | MPLELANEKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303562-B1 | ALKYLATING HYDROXYPHENYLBENZENESULFINIC/SULFONIC ACID COMPOUND WITH ALKENE OR SUBSTITUTED ALKENE TO FORM ALKYLATED PRODUCT | ENCHIRA BIOTECHNOLOGY CORPORATION | 2001-10-16 | — | — | US | disclosed |
| WO-2000042005-A1 | COMPOSITIONS COMPRISING 2-(2-HYDROXYPHENYL) BENZENESULFINATE AND ALKYL-SUBSTITUTED DERIVATIVES THEREOF | ENERGY BIOSYSTEMS CORPORATION (US) | 2000-07-20 | — | — | WO | disclosed |