SCHEMBL27324976

SCHEMBL27324976

O=CC(C[S+]=O)Cc1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.44
TDP1 Q9NUW8 1/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
CYP2C9 P11712 1/20 0.40
ACP3 P15309 1/20 0.39
MAPK1 P28482 1/20 0.38
MC5R P33032 1/20 0.38
CYP2D6 P10635 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37
SLC1A1 P43005 1/20 0.37
CA2 P00918 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8484930 0.87 CTNNB1 (0.51) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL27312637 0.79 CTNNB1 (0.40) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL27301245 0.78 CTNNB1 (0.44) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL6448370 0.77 TDP1 (0.54) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL9666926 0.77 CYP1A2 (0.47) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL6443040 0.77 CTNNB1 (0.43) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL7271887 0.77 KMT2A (0.54) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL11275502 0.76 CTNNB1 (0.51) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL6446875 0.76 CTNNB1 (0.49) CTNNB1TDP1CYP1A2ACP3SLC1A3
SCHEMBL7296607 0.75 CTNNB1 (0.41) CTNNB1TDP1CYP1A2CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1032786-A N-acyl amino acid derivative and uses thereof BANYU PHARMA CO LTD (JP) 1989-05-10 CN claimed