Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28822470 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRTHRBCYP1A2LMNA | |
| Acetic Acid SCHEMBL28100343 | 0.97 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRBCYP1A2LMNA | |
| Acetic Acid SCHEMBL30424912 | 0.92 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBCYP1A2LMNA | |
| Ether SCHEMBL27602732 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBCYP1A2LMNA | |
| Acetic Acid SCHEMBL775056 | 0.92 | ALDH1A1 (0.67) | ALDH1A1TSHRTHRBLMNAHSD17B10 | |
| Acetic Acid SCHEMBL29137469 | 0.92 | ALDH1A1 (0.67) | ALDH1A1TSHRTHRBLMNAHSD17B10 | |
| Acetic Acid SCHEMBL5086365 | 0.89 | ALDH1A1 (0.64) | ALDH1A1TSHRTHRBLMNAHSD17B10 | |
| Acetic Acid SCHEMBL11973815 | 0.89 | ALDH1A1 (0.64) | ALDH1A1TSHRTHRBLMNAHSD17B10 | |
| Acetic Acid SCHEMBL9493592 | 0.89 | ALDH1A1 (0.64) | ALDH1A1TSHRTHRBLMNAHSD17B10 | |
| Acetic Acid SCHEMBL950771 | 0.89 | ALDH1A1 (0.64) | ALDH1A1TSHRTHRBLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107879449-B | Low cost chelates compound heavy metal chelating agent and preparation method thereof and its application | 顺德职业技术学院 | 2019-11-08 | — | — | CN | claimed |
| CN-110387549-A | Inhibit the additive and method of coil of strip pickling rear surface residual ferrous powder | 武汉钢铁有限公司 | 2019-10-29 | — | — | CN | claimed |
| CN-106226509-B | A method of DSE phenomenon is induced in mouse anterior cingutate cortex | 中国人民解放军第四军医大学 | 2019-09-06 | — | — | CN | claimed |
| CN-110055288-A | A method of polyphenol compound is synthesized with novel enzyme immobilization technology | 深圳大学 | 2019-07-26 | — | — | CN | claimed |
| CN-109797593-A | The process for cleanly preparing of purified cotton under a kind of room temperature, normal pressure | 江苏三富纤维科技有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-109566599-A | A kind of exfoliated cell preservative fluid | 南京健邦锦源医疗仪器有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-108946783-A | A kind of method of purification containing gypsum raw material | 北京中金瑞丰环保科技有限公司 | 2018-12-07 | — | — | CN | claimed |
| CN-108854942-A | A kind of dry process method for preparation of modified bentonite | 福建工程学院 | 2018-11-23 | — | — | CN | claimed |
| CN-105973890-B | A kind of screening technique of active substance of plant | 西南大学 | 2018-11-13 | — | — | CN | claimed |
| CN-108752726-A | A kind of novel antibacterial EVA expanded materials and preparation method thereof | 福建三盛实业有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-1157462-C | Nano-class conversion fluorescence material on fluoride matrix and its preparing process | �廪��ѧ | 2004-07-14 | — | — | CN | claimed |
| CN-1139548-C | Multifunctional additive for cooling water system | 长岭(集团)股份有限公司 | 2004-02-25 | — | — | CN | claimed |
| CN-1376759-A | Nano-class conversion fluorescence material on fluoride matrix and its preparing process | UNIV TSINGHUA (CN) | 2002-10-30 | — | — | CN | claimed |
| CN-1089724-C | Preparation of high pure globular amorphous silicon powder | UNIV WUHAN (CN) | 2002-08-28 | — | — | CN | claimed |
| CN-1365961-A | Process for removing heavy metals from diphenylether products | TIANJIN SCIENCE AND ENGINEERIN (CN) | 2002-08-28 | — | — | CN | claimed |
| CN-1062250-C | Method for in-situ dressing surface of sol particles | DALIAN CHEMICAL PHYSICS INST (CN) | 2001-02-21 | — | — | CN | claimed |
| CN-1258648-A | Multifunctional additive for cooling water system | CHANGLING GROUP CO LTD (CN) | 2000-07-05 | — | — | CN | claimed |
| CN-1231996-A | Cleaning agent for cooling system of vehicle | BAILIWEI SCI & TECH DEV CENTER (CN) | 1999-10-20 | — | — | CN | claimed |
| CN-1188075-A | Preparation of high pure globular amorphous silicon powder | UNIV WUHAN (CN) | 1998-07-22 | — | — | CN | claimed |
| CN-1150124-A | Method for in-situ dressing surface of sol particles | DALIAN CHEMICAL PHYSICS INST (CN) | 1997-05-21 | — | — | CN | claimed |