Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | NEK1 | Q96PY6 | 3/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716438 | 0.86 | ERN1 (0.52) | ALDH1A1HPGDL3MBTL1ALOX15HTT | |
| SCHEMBL22800247 | 0.86 | KDM4E (0.46) | ALDH1A1HPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL6718025 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HPGDL3MBTL1ALOX15HTT | |
| SCHEMBL9301000 | 0.84 | TDP1 (0.45) | ALDH1A1HPGDL3MBTL1MAP2K1TDP1 | |
| SCHEMBL31218736 | 0.84 | MAPT (0.47) | ALDH1A1HPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL27928801 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HPGDL3MBTL1ALOX15HTT | |
| SCHEMBL6438132 | 0.84 | MAPT (0.47) | ALDH1A1HPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL7649536 | 0.83 | TDP1 (0.59) | ALDH1A1HPGDL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL5558179 | 0.82 | CDK8 (0.56) | ALDH1A1HPGDL3MBTL1ALOX15HTT | |
| SCHEMBL6717844 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HPGDL3MBTL1ALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1014992-B | QUINAZOLIDIONE AND PYRIDOPYRIMIDINE DIONE AND PREPARING METHOD | PFIZER (US) | 1991-12-04 | — | — | CN | disclosed |
| CN-87105791-A | Quinazoline diones and Pyridopyrimidine diketone and preparation method thereof | — | 1988-03-09 | — | — | CN | disclosed |