⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27326454 | 1.00 | — | — | |
| SCHEMBL27326455 | 1.00 | — | — | |
| SCHEMBL13144617 | 0.85 | ACHE (0.54) | — | |
| SCHEMBL18531196 | 0.85 | ACHE (0.54) | — | |
| SCHEMBL3863371 | 0.85 | ACHE (0.54) | — | |
| SCHEMBL774178 | 0.83 | ACHE (0.52) | — | |
| SCHEMBL27326103 | 0.83 | ACHE (0.52) | — | |
| SCHEMBL27326106 | 0.83 | ACHE (0.52) | — | |
| SCHEMBL19369412 | 0.81 | TP53 (0.41) | — | |
| SCHEMBL30396381 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123966-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | THIRD HARMONIC BIO, INC. (US) | 2024-06-13 | — | — | WO | disclosed |
| WO-2024124002-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | THIRD HARMONIC BIO, INC. (US) | 2024-06-13 | — | — | WO | disclosed |