Biphenyl

Biphenyl

SCHEMBL27328558

CN(C)Pc1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
TAAR1 Q96RJ0 2/20 0.41
MMP3 P08254 1/20 0.40
BCL2L1 Q07817 1/20 0.40
SLC22A2 O15244 1/20 0.37
SLC22A1 O15245 1/20 0.37
SLC22A3 O75751 1/20 0.37
SLC6A4 P31645 1/20 0.37
USP2 O75604 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NOTUM Q6P988 1/20 0.35
LSS P48449 1/20 0.34
PYCR1 P32322 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6289830 0.92 TSHR (0.36) ALDH1A1TAAR1MAPK1HSD17B10TDP1
SCHEMBL28246803 0.90 TSHR (0.35) ALDH1A1TAAR1MAPK1HSD17B10TDP1
Biphenyl SCHEMBL6740039 0.74 ALDH1A1 (0.69) ALDH1A1TAAR1MMP3BCL2L1SLC22A2
Trimethylammonium SCHEMBL27803407 0.72 ALDH1A1 (0.64) ALDH1A1TAAR1MMP3BCL2L1SLC22A2
Biphenyl SCHEMBL1160795 0.72 ALDH1A1 (0.64) ALDH1A1TAAR1MMP3BCL2L1SLC22A2
Biphenyl SCHEMBL10535523 0.69 ALDH1A1 (0.60) ALDH1A1TAAR1MMP3BCL2L1SLC22A2
Biphenyl SCHEMBL27633354 0.69 ALDH1A1 (0.60) ALDH1A1TAAR1MMP3BCL2L1SLC22A2
Tannin Pyrogallol SCHEMBL11548899 0.69 ALDH1A1 (0.60) ALDH1A1TAAR1MMP3BCL2L1SLC22A2
Biphenyl SCHEMBL27559436 0.69 ALDH1A1 (0.60) ALDH1A1TAAR1MMP3BCL2L1SLC22A2
Biphenyl SCHEMBL27559435 0.69 ALDH1A1 (0.60) ALDH1A1TAAR1MMP3BCL2L1SLC22A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1013117-B PROCESS FOR PREPARATING HARDENING PRODUCTS BASED ON OLEFINIC UNSATURATED COMPOUNDS AND COMPOUNDS CONTAINING ACTIVE HYDROGEN AND THE USE THEREOF THE SYSTEM IN DOUBLE COMPOSITIONS PAINT HOECHST AG (DE) 1991-07-10 CN disclosed
CN-86107731-A Is the method and the application of this system in double compositions paint of feedstock production cured product with alefinically unsaturated compounds with the compound that contains reactive hydrogen 1987-06-17 CN disclosed