SCHEMBL2732885

SCHEMBL2732885

O=C(Nc1ccc(Sc2nc3ccccc3s2)cc1)c1ccc(-c2ccc(C(=O)Nc3ccc(Sc4nc5ccccc5s4)cc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSPD1 P10809 2/20 0.64
▸ HSPE1 P61604 2/20 0.64
▸ CTSD P07339 2/20 0.61
▸ MMP2 P08253 1/20 0.61
▸ MMP9 P14780 1/20 0.61
▸ MMP8 P22894 1/20 0.61
▸ MMP13 P45452 1/20 0.61
▸ MAPT P10636 5/20 0.59
▸ SMN1; SMN2 Q16637 4/20 0.59
▸ MEN1 O00255 3/20 0.59
▸ KMT2A Q03164 3/20 0.59
▸ LMNA P02545 1/20 0.59
▸ GAA P10253 1/20 0.59
▸ SCD O00767 2/20 0.57
▸ NPC1 O15118 4/20 0.55
▸ RAB9A P51151 4/20 0.55
▸ NFKB1 P19838 3/20 0.55
▸ NFKB2 Q00653 3/20 0.55
▸ RELA Q04206 3/20 0.55
▸ PKM P14618 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24118880 0.93 SMN1; SMN2 (0.67) HSPD1HSPE1CTSDMMP2MMP9
SCHEMBL24118887 0.85 HSPD1 (0.73) HSPD1HSPE1CTSDMMP2MMP9
SCHEMBL24118878 0.83 HSPD1 (0.67) HSPD1HSPE1CTSDMMP2MMP9
SCHEMBL29612954 0.83 MAPT (0.63) HSPD1HSPE1CTSDMAPTSMN1; SMN2
SCHEMBL28760799 0.83 MAPT (0.63) HSPD1HSPE1CTSDMAPTSMN1; SMN2
SCHEMBL24118814 0.82 HSPD1 (0.75) HSPD1HSPE1CTSDMAPTSMN1; SMN2
SCHEMBL29612946 0.79 HSPD1 (0.56) HSPD1HSPE1CTSDMAPTSMN1; SMN2
SCHEMBL28760746 0.79 HSPD1 (0.56) HSPD1HSPE1CTSDMAPTSMN1; SMN2
SCHEMBL24118866 0.79 HSPD1 (0.67) HSPD1HSPE1CTSDMAPTSMN1; SMN2
SCHEMBL20591228 0.78 MAPT (0.56) HSPD1HSPE1CTSDMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8313814-B2 Cellulose acylate film, method of producing the same, cellulose derivative film, optically compensatory film using the same, optically-compensatory film incorporating polarizing plate, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-11-20 — — US disclosed
US-8313814-B2 Cellulose acylate film, method of producing the same, cellulose derivative film, optically compensatory film using the same, optically-compensatory film incorporating polarizing plate, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-11-20 — — US disclosed
US-8247041-B2 Cellulose acylate film FUJIFILM CORPORATION (JP) 2012-08-21 — — US disclosed
US-8247041-B2 Cellulose acylate film FUJIFILM CORPORATION (JP) 2012-08-21 — — US disclosed
US-8197726-B2 Cellulose acylate film and method for producing same FUJIFILM CORPORATION (JP) 2012-06-12 — — US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 — — US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 — — US disclosed
US-7981489-B2 Optical compensation sheet and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-07-19 — — US disclosed
US-7981489-B2 Optical compensation sheet and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-07-19 — — US disclosed
US-20110128478-A1 POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD OF MANUFACTURING PROTECTIVE FILM FOR POLARIZING PLATE KONICA MINOLTA OPTO, INC. (JP) 2011-06-02 — — US disclosed
US-20080111954-A1 Cellulose Acylate Film And Method For Producing Same FUJIFILM CORPORATION (JP) 2008-05-15 — — US disclosed
US-20080111954-A1 Cellulose Acylate Film And Method For Producing Same FUJIFILM CORPORATION (JP) 2008-05-15 — — US disclosed
US-20080113118-A1 cellulose ester films produced by melt-casting, having microstructure projections and depressions, used as polarizing layers and substrates for optically-compensatory films for liquid crystal display plates and antireflection films, which reduces distortion of displays FUJIFILM CORPORATION (JP) 2008-05-15 — — US disclosed
WO-2007111388-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-10-04 — — WO disclosed
WO-2007086538-A1 RETARDATION PLATE, POLARIZER PLATE, AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPOTATION (JP) 2007-08-02 — — WO disclosed
WO-2007061139-A1 CELLULOSE ACYLATE FILM, METHOD OF PRODUCING THE SAME, CELLULOSE DERIVATIVE FILM, OPTICALLY COMPENSATORY FILM USING THE SAME, OPTICALLY-COMPENSATORY FILM INCORPORATING POLARIZING PLATE, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-05-31 — — WO disclosed
US-20070077373-A1 Polymer film and polarizing plate and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 — — US disclosed
US-20070077373-A1 Polymer film and polarizing plate and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 — — US disclosed
US-20070048458-A1 Optical film, method of producing the same, optical compensatory film, polarizing film, and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-03-01 — — US disclosed
US-20070048458-A1 Optical film, method of producing the same, optical compensatory film, polarizing film, and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-03-01 — — US disclosed
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