Quinoline

Quinoline

SCHEMBL27328895

F.c1ccc2ncccc2c1

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.94
NPC1 O15118 2/20 0.56
POLB P06746 1/20 0.56
RAB9A P51151 1/20 0.56
CYP3A4 P08684 3/20 0.54
MAPT P10636 4/20 0.52
HTT P42858 3/20 0.52
KDM4E B2RXH2 3/20 0.52
CASP1 P29466 2/20 0.52
TP53 P04637 2/20 0.52
HSP90AA1 P07900 2/20 0.52
TSHR P16473 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MEN1 O00255 1/20 0.52
CASP7 P55210 1/20 0.52
KMT2A Q03164 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52
NR4A2 P43354 1/20 0.52
HSP90AB1 P08238 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL5875146 1.00 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL28273361 1.00 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL18804794 1.00 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL27689007 0.97 ALDH1A1 (0.90) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL28292617 0.97 ALDH1A1 (0.90) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL27279184 0.97 ALDH1A1 (0.90) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL27879213 0.97 ALDH1A1 (0.90) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL28131670 0.97 ALDH1A1 (0.90) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL29822171 0.97 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL29349552 0.97 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 515 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106167486-B Monocycle class gyrase and topoisomerase I V inhibitor 北京四环制药有限公司 2019-06-14 CN claimed
CN-109725142-A The enzyme linked immunological kit of detection fluo quinolone drug residual and application and detection method 国家食品安全风险评估中心 2019-05-07 CN claimed
CN-109689090-A anti-O2 antibodies and uses thereof 免疫医疗有限责任公司 2019-04-26 CN claimed
CN-109640948-A Chemical composition that 利物浦大学 2019-04-16 CN claimed
CN-109438559-A A kind of polypeptide of anti-Multi-drug resistant Acinetobacter baumannii 中国人民解放军陆军军医大学 2019-03-08 CN claimed
CN-109369677-A A kind of pair-fluoquinolone oxadiazoles ureas N- methyl Ciprofloxacin derivative and its preparation method and application 郑州工业应用技术学院 2019-02-22 CN claimed
CN-109369676-A A kind of pair-fluoquinolone oxadiazoles ureas N- acetyl norfloxacin derivatives and its preparation method and application 郑州工业应用技术学院 2019-02-22 CN claimed
CN-109336902-A A kind of pair-fluoquinolone oxadiazoles ureas N- acetyl group ciprofloxacin derivatives and its preparation method and application 郑州工业应用技术学院 2019-02-15 CN claimed
CN-109310644-A Anti-infective composition comprising plant glycogen nano particle 奇迹连结生物技术公司 2019-02-05 CN claimed
CN-109221156-A Insecticidal and acaricidal composition of the one kind containing fungicide or bactericidal (virus) agent 沈阳中化农药化工研发有限公司 2019-01-18 CN claimed
CN-105832946-A Medicine for treating human cancer and production method thereof 崔明华 2016-08-10 CN claimed
CN-105792651-A Pesticidal compositions and related methods 美国陶氏益农公司 2016-07-20 CN claimed
CN-105766996-A Drug for crop cancer prevention and production method thereof 崔明华 2016-07-20 CN claimed
CN-105766990-A Bismuth-thiols As Antiseptics For Epithelial Tissues, Acute And Chronic Wounds, Bacterial Biofilms And Other Indications 微生物公司 2016-07-20 CN claimed
CN-104497014-B A kind of chiral fluoroquinolone C-3 condensed hetero ring α, alpha, beta-unsaturated ketone derivant and its preparation method and application 河南大学 2016-07-20 CN claimed
CN-105482687-A Manufacture method for long-acting wide-spectrum antibacterial anticorrosion nanometer spraying bubble agent WANG PING 2016-04-13 CN claimed
CN-105358573-A Anti-muramic acid antibodies and conjugates GENENTECH INC 2016-02-24 CN claimed
CN-105123757-A Green multifunctional bactericide and preparation method thereof CUI MINGHUA 2015-12-09 CN claimed
CN-101720187-A Method for improving quality of plant flower buds BAYER CROPSCIENCE SA 2010-06-02 CN claimed
CN-101516369-A Pyridinone diketo acids: inhibitors of HIV replication in combination therapy UNIV GEORGIA (US) 2009-08-26 CN claimed