SCHEMBL27329103

SCHEMBL27329103

C1CCC(NC2CCCCC2)CC1.NC(=S)S

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
HSD17B10 Q99714 1/20 0.60
CYP3A4 P08684 2/20 0.48
TP53 P04637 1/20 0.48
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
SMN1; SMN2 Q16637 5/20 0.42
NPC1 O15118 4/20 0.40
RAB9A P51151 3/20 0.40
MAPK1 P28482 1/20 0.40
DUSP3 P51452 1/20 0.40
PTPN5 P54829 1/20 0.40
PTPN11 Q06124 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
EPHX1 P07099 5/20 0.37
ADH1B P00325 1/20 0.37
ADH1C P00326 1/20 0.37
ADH1A P07327 1/20 0.37
ADH4 P08319 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28908738 0.87 ALDH1A1 (0.63) ALDH1A1HSD17B10CYP3A4TP53LMNA
SCHEMBL16334677 0.81 ALDH1A1 (0.44) ALDH1A1HSD17B10CYP3A4TP53LMNA
Urea SCHEMBL27639951 0.79 ALDH1A1 (0.67) ALDH1A1HSD17B10CYP3A4LMNASMN1; SMN2
SCHEMBL18657086 0.78 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4TP53SMN1; SMN2
SCHEMBL24771539 0.78 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4TP53SMN1; SMN2
SCHEMBL24771540 0.78 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4TP53SMN1; SMN2
SCHEMBL24839013 0.78 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4TP53SMN1; SMN2
SCHEMBL21375316 0.78 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4TP53SMN1; SMN2
SCHEMBL20733078 0.78 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4TP53SMN1; SMN2
SCHEMBL18657085 0.78 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4TP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1041738-C Compositions of vulcanize rubbers MITSUI PETROCHEMICAL IND (JP) 1999-01-20 CN disclosed
CN-1027378-C Vulcanizable rubber composition MITSUI PETROCHEMICAL IND (JP) 1995-01-11 CN disclosed
CN-1069747-A Compositions of vulcanize rubbers MITSUI PETROCHEMICAL INDUSTXIE (JP) 1993-03-10 CN disclosed
CN-1037719-A VULCANIZABLE RUBBER COMPOSITION MITSUI PETROCHEMICAL IND (JP) 1989-12-06 CN disclosed