Paroxypropione

Paroxypropione

SCHEMBL27329381

CCC(=O)c1ccc(O)cc1.Cc1ccccc1

nearest known ligand 0.61

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
RAB9A P51151 4/20 0.56
NPC1 O15118 3/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
HSD17B3 P37058 8/20 0.53
ALDH1A1 P00352 2/20 0.51
GAA P10253 1/20 0.49
HTT P42858 1/20 0.49
ESR1 P03372 2/20 0.49
CYP19A1 P11511 1/20 0.49
ESR2 Q92731 1/20 0.49
CES2 O00748 1/20 0.48
DPP4 P27487 1/20 0.47
LMNA P02545 1/20 0.47
HSD17B10 Q99714 1/20 0.47
HSD11B1 P28845 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paroxypropione SCHEMBL440470 0.86 HSD17B3 (0.68) MAPTSMN1; SMN2L3MBTL1RAB9ANPC1
Paroxypropione SCHEMBL11689689 0.82 HSD17B3 (0.69) MAPTSMN1; SMN2L3MBTL1RAB9ANPC1
SCHEMBL507067 0.82 GSK3B (0.64) MAPTSMN1; SMN2L3MBTL1RAB9ANPC1
Paraben SCHEMBL388088 0.80 CA12 (0.70) MAPTSMN1; SMN2RAB9ANPC1MEN1
SCHEMBL12004592 0.80 MAPT (0.70) MAPTSMN1; SMN2L3MBTL1RAB9ANPC1
Hydrochloric Acid SCHEMBL30478406 0.80 GSK3B (0.61) MAPTSMN1; SMN2L3MBTL1RAB9ANPC1
Propiophenone SCHEMBL318818 0.80 SMN1; SMN2 (0.75) MAPTSMN1; SMN2L3MBTL1RAB9ANPC1
Propiophenone SCHEMBL76464 0.80 SMN1; SMN2 (0.75) MAPTSMN1; SMN2L3MBTL1RAB9ANPC1
Propiophenone SCHEMBL14244535 0.80 SMN1; SMN2 (0.75) MAPTSMN1; SMN2L3MBTL1RAB9ANPC1
Ethylparaben SCHEMBL163746 0.79 ESR1 (0.79) MAPTSMN1; SMN2RAB9ANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1036276-A Make the method for erect image and negative-appearing image with the static main leaf of photo-hardening DU PONT (US) 1989-10-11 CN disclosed