Paroxypropione

Paroxypropione

SCHEMBL440470

CCC(=O)c1ccc(O)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 8/20 0.68
PTPN1 P18031 1/20 0.60
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60
MAPT P10636 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
ESR1 P03372 4/20 0.58
ESR2 Q92731 4/20 0.58
ALDH1A1 P00352 2/20 0.58
LMNA P02545 2/20 0.58
MEN1 O00255 1/20 0.58
NR1I2 O75469 1/20 0.58
USP2 O75604 1/20 0.58
NR3C1 P04150 1/20 0.58
TP53 P04637 1/20 0.58
CYP1A2 P05177 1/20 0.58
FYN P06241 1/20 0.58
PGR P06401 1/20 0.58
CHRM2 P08172 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paroxypropione SCHEMBL11689689 0.95 HSD17B3 (0.69) HSD17B3PTPN1NPC1RAB9AMAPT
SCHEMBL12004592 0.93 MAPT (0.70) HSD17B3PTPN1NPC1RAB9AMAPT
Paroxypropione SCHEMBL27862463 0.89 NPC1 (0.65) HSD17B3PTPN1NPC1RAB9AMAPT
SCHEMBL8051337 0.89 SMN1; SMN2 (0.70) HSD17B3NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL16125328 0.88 HSD17B3 (0.55) HSD17B3PTPN1NPC1RAB9AMAPT
SCHEMBL6061938 0.88 PARP10 (0.58) HSD17B3NPC1RAB9AMAPTSMN1; SMN2
Paroxypropione SCHEMBL27329381 0.86 MAPT (0.61) HSD17B3NPC1RAB9AMAPTSMN1; SMN2
Ethyne SCHEMBL8050785 0.84 SMN1; SMN2 (0.64) HSD17B3NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL6890145 0.82 HSD17B3 (0.59) HSD17B3PTPN1NPC1RAB9AMAPT
SCHEMBL10389933 0.82 SMN1; SMN2 (0.83) HSD17B3PTPN1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2069 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4525938-B1 RADIOPHARMACEUTICAL COMPLEXES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND ITS COMBINATIONS BAYER AG (DE) 2026-03-11 EP claimed
US-20250319216-A1 RADIOPHARMCEUTICAL COMPLEXES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND ITS COMBINATIONS BAYER AG (DE) 2025-10-16 US claimed
US-20250144187-A1 COMBINATION OF HYDROLASES AND ANTI-MICROORGANISM DRUGS AND USES THEREOF Centre for Eye and Vision Research Limited (CN) 2025-05-08 US claimed
WO-2025082408-A1 COMBINATION OF HYDROLASES AND ANTI-MICROORGANISM DRUGS AND USES THEREOF Centre for Eye and Vision Research Limited (CN) 2025-04-24 WO claimed
CN-119751230-A Efficient synthesis process of p-hydroxy propiophenone 安徽英瑞骐生物科技有限公司 2025-04-04 CN claimed
EP-4525938-A1 RADIOPHARMACEUTICAL COMPLEXES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND ITS COMBINATIONS Bayer Aktiengesellschaft (DE) 2025-03-26 EP claimed
CN-115521249-B 2- [4- (1-Oxo alkyl) phenoxy ] -3-picolinic acid, preparation method and application thereof 沈阳兴齐眼药股份有限公司 2025-03-11 CN claimed
CN-119504370-A Phenol derivative 4-ethylphenol and 4-acetonylphenol, preparation method and application thereof 中国科学院昆明植物研究所 2025-02-25 CN claimed
US-20250009655-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC 2025-01-09 US claimed
US-20240343738-A1 Method for preparing pranoprofen and composition comprising pranoprofen and impurity SHENYANG XINGQI PHARMACEUTICAL CO., LTD. (CN) 2024-10-17 US claimed
EP-0038071-B1 NEW UNLABELLED AND RADIOACTIVE LABELLED DERIVATIVES OF BUTYLAMINO PROPIOPHENONE, THEIR PREPARATION, IMMUNOGENS OBTAINED FROM THE UNLABELLED DERIVATIVES AND A PROCESS FOR IMMUNOGEN PREPARATION, ANTISERA RAISED USING THE IMMUNOGENS AND A METHOD FOR RAISING ANTISERA, A RADIOIMMUNOASSAY METHOD AND A TEST KIT FOR USE IN THE ASSAY METHOD THE WELLCOME FOUNDATION LIMITED (GB) 1984-11-14 EP claimed
EP-0112588-A2 4-Hydroxy-alpha-ethyl benzhydroles, process for their preparation and medicines containing these compounds RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1984-07-04 EP claimed
EP-0112586-A2 Substituted 4'-hydroxy-alpha-ethyl benzhydroles for use as medicaments RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1984-07-04 EP claimed
US-4448869-A HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE FUJI PHOTO FILM CO., LTD. (JP) 1984-05-15 US claimed
US-4377691-A Process for the preparation of 1-(4-hydroxyphenyl)-2-(4-benzylpiperidino)-1-propanol and acid-addition salts thereof KABUSHIKI KAISHA COSMOS ENTERPRISE (JP) 1983-03-22 US claimed
EP-0056283-A1 Ion sensor TERUMO CORPORATION (JP) 1982-07-21 EP claimed
US-4334054-A ANODIZING, PAINTS AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1982-06-08 US claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
EP-0000107-A1 Metallic or metallised article coated with a polyphenylene oxide film carrying reactive groups, its electrochemical preparation and its use ANVAR Agence Nationale de Valorisation de la Recherche (FR) 1978-12-20 EP claimed
US-3947603-A PHENOLS FIRMENICH & CIE (CH) 1976-03-30 US claimed