Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 3/20 | 0.37 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27329309 | 0.91 | GCGR (0.35) | XDHKDM4E | |
| SCHEMBL27329419 | 0.87 | HAVCR2 (0.38) | HAVCR2XDHKDM4EALDH1A1HPGD | |
| SCHEMBL30992431 | 0.84 | HAVCR2 (0.41) | HAVCR2HTTXDHKDM4EALDH1A1 | |
| SCHEMBL27329681 | 0.84 | CXCR2 (0.33) | HAVCR2 | |
| SCHEMBL27329413 | 0.84 | HAVCR2 (0.37) | HAVCR2XDHKDM4EALDH1A1HPGD | |
| SCHEMBL27329901 | 0.79 | XDH (0.36) | XDH | |
| SCHEMBL27329052 | 0.78 | BCHE (0.40) | LIPEHTTBCHEACHEXDH | |
| SCHEMBL27329409 | 0.78 | GCGR (0.35) | HTTXDHKDM4E | |
| SCHEMBL30992650 | 0.77 | HAVCR2 (0.43) | HAVCR2HTTXDHKDM4EALDH1A1 | |
| SCHEMBL27329047 | 0.77 | HPGD (0.40) | HTTXDHKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129881-A1 | COMPOUNDS, COMPOSITIONS, AND MEZHODS OF TREATING DISORDERS ASSOCIATED WITH PROTEIN MISFOLDING | WAVEBREAK THERAPEUTICS LIMITED (US) | 2024-06-20 | — | — | WO | disclosed |