SCHEMBL27329642

SCHEMBL27329642

Fc1cccc(-c2cccc3c2sc2c(C4=CC=CCC4)cccc23)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.34
HTR7 P34969 1/20 0.34
ALOX5 P09917 1/20 0.33
RIPK1 Q13546 1/20 0.33
SLC9A1 P19634 1/20 0.33
PIM1 P11309 3/20 0.33
CDK2 P24941 3/20 0.33
GSK3B P49841 3/20 0.33
PRKACA P17612 2/20 0.33
IRAK4 Q9NWZ3 2/20 0.33
CDC7 O00311 1/20 0.33
ROCK2 O75116 1/20 0.33
MAP4K4 O95819 1/20 0.33
HIPK2 Q9H2X6 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
PLK4 O00444 2/20 0.32
AURKA O14965 2/20 0.32
DAPK3 O43293 2/20 0.32
CHEK2 O96017 2/20 0.32
CDK1 P06493 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24849744 0.85 LIMK1 (0.41) ALOX5LIMK1
SCHEMBL25086344 0.83 ALOX5 (0.37) ALOX5LIMK1
SCHEMBL13139758 0.78 CHRNB4 (0.40) HTR1AHTR7HSD17B1HSD17B2GABRP
SCHEMBL24254929 0.78 LIMK1 (0.30) LIMK1
SCHEMBL17816858 0.76 ALOX5 (0.43) ALOX5MEN1MAPTKMT2A
SCHEMBL25943284 0.70 ALOX5 (0.45) ALOX5MAPT
SCHEMBL22781197 0.68 ALOX5 (0.42) ALOX5MEN1KMT2A
SCHEMBL26039917 0.68 ALOX5 (0.32) ALOX5
SCHEMBL19444850 0.67 ALOX5 (0.41) ALOX5
SCHEMBL22293499 0.67 ALOX5 (0.39) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023234603-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME (주)피엔에이치테크 2023-12-07 WO disclosed