Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | CCL5 | P13501 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL824146 | 0.90 | EPHX2 (0.39) | EPHX2HCRTR2CCL5 | |
| SCHEMBL20233006 | 0.83 | EPHX2 (0.35) | EPHX2TSHRHCRTR2CCL5 | |
| SCHEMBL7130917 | 0.79 | EPHX2 (0.53) | EPHX2CHRM4TSHRLPAR1LPAR2 | |
| SCHEMBL10232856 | 0.78 | EPHX2 (0.33) | EPHX2HCRTR2CCL5 | |
| SCHEMBL22171140 | 0.78 | EPHX2 (0.33) | EPHX2HCRTR2CCL5 | |
| SCHEMBL24267436 | 0.78 | EPHX2 (0.33) | EPHX2HCRTR2CCL5 | |
| SCHEMBL8263019 | 0.78 | EPHX2 (0.50) | EPHX2CHRM4TSHRL3MBTL1 | |
| SCHEMBL21670596 | 0.77 | EPHX2 (0.52) | EPHX2CHRM4TSHRL3MBTL1GAA | |
| SCHEMBL5289842 | 0.77 | EPHX2 (0.52) | EPHX2CHRM4TSHRL3MBTL1GAA | |
| SCHEMBL17172981 | 0.76 | CCL5 (0.31) | EPHX2TSHRHCRTR2CCL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235880-A1 | CD38 MODULATORS AND USES THEREOF | AEOVIAN PHARMACEUTICALS, INC. (US) | 2023-12-07 | — | — | WO | disclosed |