Sugi Predict

Sugi Predict / Targets / CCL5

CCL5

C-C motif chemokine 5 · P13501 · CCL5 on Sugi Atlas →

1,675 patent compounds predicted against CCL5, 952 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL3269877 SCHEMBL3269877 1.00 20/20
SCHEMBL3270176 SCHEMBL3270176 1.00 20/20
SCHEMBL3270317 SCHEMBL3270317 1.00 20/20
SCHEMBL3270350 SCHEMBL3270350 1.00 20/20
SCHEMBL3270470 SCHEMBL3270470 1.00 20/20
SCHEMBL3270840 SCHEMBL3270840 1.00 20/20
SCHEMBL3271194 SCHEMBL3271194 1.00 20/20
SCHEMBL3271203 SCHEMBL3271203 1.00 20/20
SCHEMBL3271224 SCHEMBL3271224 1.00 20/20
SCHEMBL3271270 SCHEMBL3271270 1.00 20/20
SCHEMBL3271438 SCHEMBL3271438 1.00 20/20
SCHEMBL3271759 SCHEMBL3271759 1.00 20/20
SCHEMBL3271898 SCHEMBL3271898 1.00 20/20
SCHEMBL3271952 SCHEMBL3271952 1.00 20/20
SCHEMBL3272404 SCHEMBL3272404 1.00 20/20
SCHEMBL3272743 SCHEMBL3272743 1.00 20/20
SCHEMBL3272910 SCHEMBL3272910 1.00 20/20
SCHEMBL3273635 SCHEMBL3273635 1.00 20/20
SCHEMBL3271763 SCHEMBL3271763 0.90 20/20
SCHEMBL3272747 SCHEMBL3272747 0.88 20/20

Clinical trials — most relevant to CCL5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Allopurinol on Inflammation and Ultrasonographic Changes in People With Elevated Uric Acid But no Symptoms PHASE3UNKNOWN
Efficacy of Ibuprofen Chronotherapy in Healing After Surgical Extraction of the Mandibular Third Molar PHASE2/PHASE3UNKNOWN
Leronlimab in Moderately Ill Patients With COVID-19 Pneumonia PHASE3SUSPENDED
Leronlimab in Patients With Coronavirus Disease 2019 (COVID-19) With Need for Mechanical Ventilation or Extracorporeal Membrane Oxygenation PHASE3SUSPENDED
Safety and Efficacy Study of Intravenous Immunoglobulin to Treat Japanese Encephalitis PHASE2COMPLETED
Effects of Maraviroc (MVC) on HIV-related Kaposi's Sarcoma (KS) PHASE2COMPLETED
Safety Study of a Chemokine Receptor (CXCR4) Antagonist in Multiple Myeloma Patients PHASE1/PHASE2COMPLETED
A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL) PHASE1RECRUITING
Maraviroc in Patients With Moderate and Severe COVID-19 PHASE1COMPLETED
Value of Various Chemokines in the Detection and Follow up of RCC nanUNKNOWN
Measuring the Healthy Pediatric Inflammatory Response to Vaccination. nanENROLLING_BY_INVITATION
Evaluating Urinary CXCL10 for Enhanced Detection of Acute Rejection in Kidney Transplant Patients With Low DD-CFDNA nanRECRUITING
Characterization of Microbiological and Genetic Features in Prostate Cancer and Their Association with Disease Stage nanENROLLING_BY_INVITATION
Genetic Polymorphism Associated With Coronary Heart Disease Susceptibility and Variability of Clopidogrel Response nanACTIVE_NOT_RECRUITING
The Role of MMPs in the CXCL12-Induced Invasion of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma nanUNKNOWN
Evaluation of Macrophage Inflammatory Protein-1α as a Periodontal Disease Biomarker nanCOMPLETED
Inflammatory Biomarkers in Psychogenic Non-epileptic Seizure nanUNKNOWN
The Role of SDF-1/CXCR4 in Metastasis of Oral Squamous Cell Carcinoma nanUNKNOWN
Inflammatory Biomarkers in Seizure nanUNKNOWN
C-X-C Chemokine Receptor 4 in Chronic Lymphocytic Leukemia nanUNKNOWN
The Role of Stromal Cell-Derived Factor-1 (SDF-1)/CXC Chemokine Receptor 4 (CXCR4) in Metastasis of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma nanUNKNOWN
Immunology Dysregulation in Lymphadenitis Tuberculosis : An Observational Study Using Patient' Block Paraffins 2019 Until 2021 nanCOMPLETED
Circular RNA and Chemerin in Breast Cancer Patient nanUNKNOWN
Inflammatory Cytokines in GCF and Placental Tissues in Chronic Periodontitis Patients With Preterm Delivery nanCOMPLETED
Replacement of Vitamin D in Patients With Active Tuberculosis nanCOMPLETED
Phenotyping Circulating and Lung Resident Eosinophils in Severe Asthma (P-CLESA) nanUNKNOWN
Detection of Circulating Biomarkers of Immunogenic Cell Death nanCOMPLETED
Ankylosing Spondylitis nanNOT_YET_RECRUITING
Early Regenerative Intervention for Post-Traumatic Osteoarthritis nanUNKNOWN
Monocyte Chemoattractant Protein-1 in Psoriatic Arthritis Patients nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a CCL5 binder may also engage these)

ProteinNameSimilarity
O97919 — 0.998 O97919 →
P97272 — 0.997 P97272 →
Q8HYQ1 — 0.996 Q8HYQ1 →
P50231 — 0.990 P50231 →
Q8MKD0 — 0.990 Q8MKD0 →
P30882 — 0.989 P30882 →
P50229 — 0.986 P50229 →
Q8HYQ3 — 0.986 Q8HYQ3 →
Q90826 — 0.985 Q90826 →
Q17QA1 — 0.984 Q17QA1 →
P14097 — 0.984 P14097 →
P13236 — 0.983 P13236 →
Q8HYS0 — 0.982 Q8HYS0 →
P50230 — 0.981 P50230 →
P10147 — 0.981 P10147 →
P10855 — 0.981 P10855 →
Q8HYQ2 — 0.981 Q8HYQ2 →
P46632 — 0.980 P46632 →
Q68AZ0 — 0.979 Q68AZ0 →
Q8NHW4 — 0.979 Q8NHW4 →
P16619 — 0.977 P16619 →
Q711P4 — 0.976 Q711P4 →
Q5I1Z0 — 0.974 Q5I1Z0 →
Q8SQA6 — 0.974 Q8SQA6 →
Q68A92 — 0.969 Q68A92 →
Q8SQ40 — 0.965 Q8SQ40 →
Q91ZL1 — 0.961 Q91ZL1 →
O46676 — 0.948 O46676 →
O46677 — 0.945 O46677 →
P19875 — 0.945 P19875 →