Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209407 | 0.80 | TSHR (0.48) | ARKDM4EHSD17B10SLC6A4ALDH1A1 | |
| SCHEMBL9331677 | 0.80 | ESR1 (0.52) | ARKDM4EHSD17B10ALDH1A1TDP1 | |
| SCHEMBL12828098 | 0.79 | SMN1; SMN2 (0.51) | ARKDM4EALDH1A1TDP1TSHR | |
| SCHEMBL14805708 | 0.76 | AR (0.63) | ARKDM4ETSHRMAPTCYP1A2 | |
| SCHEMBL29960 | 0.74 | SLC6A4 (0.35) | ARKDM4EHSD17B10SLC6A4 | |
| SCHEMBL4907753 | 0.74 | ALDH1A1 (0.43) | HSD17B10ALDH1A1TDP1TSHRMAPT | |
| SCHEMBL30832958 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRMAPTCYP1A2 | |
| SCHEMBL47860 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRMAPTCYP1A2 | |
| SCHEMBL333951 | 0.72 | SLC6A4 (0.47) | ARKDM4EHSD17B10SLC6A4ALDH1A1 | |
| SCHEMBL20345294 | 0.72 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927076-B2 | HSP90B N-terminal isoform-selective inhibitors | UNIVERSITY OF KANSAS (US) | 2021-02-23 | — | — | US | disclosed |
| US-8088805-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927076-B2 | HSP90B N-terminal isoform-selective inhibitors | HSP90AB1, HSP90AB2P, HSP90B1 | AR 2291/4885KDM4E 3915/4885HSD17B10 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.