Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2690794 | 0.87 | MAPK1 (0.40) | NPC1RAB9AMAPK1ADORA3CYP2A6 | |
| SCHEMBL23460285 | 0.87 | MAPK1 (0.40) | NPC1RAB9AMAPK1ADORA3CYP2A6 | |
| SCHEMBL15910364 | 0.86 | GRM1 (0.38) | NPC1RAB9AMAPK1ADORA3CYP2A6 | |
| SCHEMBL15363475 | 0.84 | DGAT1 (0.38) | NPC1RAB9AMAPK1ADORA3CYP2A6 | |
| SCHEMBL16269898 | 0.84 | NPC1 (0.41) | NPC1RAB9AMAPK1ADORA3ALDH1A1 | |
| SCHEMBL16653197 | 0.84 | NPC1 (0.41) | NPC1RAB9AMAPK1ADORA3CYP2A6 | |
| SCHEMBL18627095 | 0.84 | GRM1 (0.40) | NPC1RAB9AMAPK1ALDH1A1HTT | |
| SCHEMBL18622368 | 0.84 | DGAT1 (0.38) | NPC1RAB9AMAPK1ADORA3CYP2A6 | |
| SCHEMBL14904618 | 0.83 | NPC1 (0.40) | NPC1RAB9AMAPK1ADORA3CYP2A6 | |
| SCHEMBL14904700 | 0.83 | NPC1 (0.40) | NPC1RAB9AMAPK1ADORA3CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852284-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | Dow AgroSciences LLC (US) | 2015-04-01 | — | — | EP | disclosed |
| EP-2775843-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | Dow AgroSciences LLC (US) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013162715-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-10-31 | — | — | WO | disclosed |
| EP-2635278-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | Dow AgroSciences LLC (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2013062981-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | WO | disclosed |
| WO-2012061290-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-10 | — | — | WO | disclosed |