Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12506518 | 0.80 | KDM4E (0.54) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL11854791 | 0.78 | SIRT2 (0.48) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL31219282 | 0.77 | PARP1 (0.48) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL6428552 | 0.77 | PARP1 (0.48) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL10550088 | 0.75 | SMN1; SMN2 (0.61) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL2731836 | 0.74 | TDP1 (0.62) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL13180854 | 0.71 | HSD17B10 (0.53) | KDM4EHPGDKMT2AALDH1A1HSD17B10 | |
| SCHEMBL22215814 | 0.70 | CYP3A4 (0.50) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL6827523 | 0.69 | CYP3A4 (0.54) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL14846515 | 0.69 | KDM4E (0.51) | KDM4EHPGDKMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054332-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |