Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31219282 | 1.00 | PARP1 (0.48) | PARP1KDM4EALDH1A1HPGDTP53 | |
| SCHEMBL1780398 | 0.82 | TP53 (0.51) | KDM4EALDH1A1TP53TSHRMEN1 | |
| SCHEMBL663628 | 0.80 | LMNA (0.44) | PARP1KDM4EALDH1A1HPGDTP53 | |
| SCHEMBL27835721 | 0.79 | TP53 (0.51) | KDM4EALDH1A1TP53TSHRMEN1 | |
| SCHEMBL28147868 | 0.79 | MTNR1A (0.44) | PARP1KDM4EALDH1A1HPGDTP53 | |
| SCHEMBL28147782 | 0.79 | LMNA (0.43) | PARP1KDM4EALDH1A1HPGDTP53 | |
| SCHEMBL2497590 | 0.78 | LMNA (0.43) | PARP1KDM4EALDH1A1HPGDTP53 | |
| SCHEMBL11803055 | 0.78 | KDM4E (0.58) | PARP1KDM4EALDH1A1HPGDTP53 | |
| SCHEMBL11667512 | 0.77 | LMNA (0.42) | PARP1KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL668767 | 0.77 | MEN1 (0.58) | KDM4EALDH1A1TP53NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5140101-A | — | — | None | — | — | JP | disclosed |
| JP-10168059-A | — | — | None | — | — | JP | disclosed |
| US-20140288050-A1 | MODULATORS OF OPIOID RECEPTORS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS, INC. | 2014-09-25 | — | — | US | disclosed |
| US-20050009903-A1 | CB2-selective cannabinoid analogues | CLEMSON UNIVERSITY | 2005-01-13 | — | — | US | disclosed |
| JP-H10168059-A | PRODUCTION OF 1-ALKYL-2-METHYLINDOLE | YAMAMOTO CHEM INC | 1998-06-23 | — | — | JP | disclosed |
| US-5410030-A | Nucleic acid stains | MOLECULAR PROBES, INC. (US) | 1995-04-25 | — | — | US | disclosed |
| JP-H05140101-A | PRODUCTION OF 1-ALKYL-2-METHYLINDOLE | YAMAMOTO CHEM INC | 1993-06-08 | — | — | JP | disclosed |
| US-4895958-A | CHROMOGENS, IMAGES, PRESSURE SENSITIVE AND HEAT RESPONSIVE CARBONLESS DUPLICATING | HILTON DAVIS CO. (US) | 1990-01-23 | — | — | US | disclosed |
| US-4795736-A | AMINOPHENYL PHENYLSULFONYL PROPENE/1-/ | HILTON DAVIS CO. (US) | 1989-01-03 | — | — | US | disclosed |
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4322352-A | Indolyl phthalide compounds | STERLING DRUG INC. (US) | 1982-03-30 | — | — | US | disclosed |
| US-4307018-A | CHROMOGENS FOR COPYING SYSTEMS | STERLING DRUG INC. (US) | 1981-12-22 | — | — | US | disclosed |
| US-4275121-A | Carbonless duplicating and marking systems utilizing indolyl-substituted furanone color formers | STERLING DRUG INC. (US) | 1981-06-23 | — | — | US | disclosed |
| US-4257954-A | INDOLYL-PHENYLSULFONYL-PHENYL METHANE | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4251446-A | COLOR PRECURSORS | STERLING DRUG INC. (US) | 1981-02-17 | — | — | US | disclosed |
| US-4189171-A | PRESSURE SENSITIVE, THERMAL AND HECTOGRAPHIC SYSTEMS | STERLING DRUG INC. (US) | 1980-02-19 | — | — | US | disclosed |
| US-4102893-A | Process for the manufacture of color formers of indoles and anhydrides of aromatic or heteroaromatic, vicinal dicarboxylic acids, new color formers of these classes of substance and their use | CIBA-GEIGY AG (CH) | 1978-07-25 | — | — | US | disclosed |
| US-4075224-A | 3,5-Bis (indolyl)-5-(indolyl)-2(5H)-furanones | STERLING DRUG INC. (US) | 1978-02-21 | — | — | US | disclosed |
| US-4022802-A | INDOLES, ALKALI HYDROXIDE; ALKYLATION | CIBA-GEIGY AG (CH) | 1977-05-10 | — | — | US | disclosed |
| US-3969346-A | Naphtholactamcarbinols color formers, their manufacture and use in pressure-sensitive or thermoreactive recording material | CIBA-GEIGY CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009903-A1 | CB2-selective cannabinoid analogues | CNR2, CNR1, GPR68 | PARP1 1518/4885KDM4E 2063/4885ALDH1A1 3475/4885 |
| US-20140288050-A1 | MODULATORS OF OPIOID RECEPTORS AND METHODS OF USE THEREOF | OPRM1, OPRK1, OPRL1 | PARP1 4137/4885KDM4E 3046/4885ALDH1A1 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.