Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811884 | 0.73 | ESR1 (0.53) | TSHRL3MBTL1TDP1ESR1LMNA | |
| SCHEMBL13416260 | 0.73 | TSHR (0.51) | TSHRL3MBTL1TDP1ESR1LMNA | |
| SCHEMBL448074 | 0.73 | TSHR (0.59) | TSHRL3MBTL1TDP1ESR1LMNA | |
| SCHEMBL28424839 | 0.70 | TSHR (0.56) | TSHRL3MBTL1TDP1ESR1LMNA | |
| SCHEMBL8549818 | 0.69 | TSHR (0.59) | TSHRL3MBTL1TDP1ESR1LMNA | |
| SCHEMBL28433114 | 0.69 | HDAC4 (0.59) | TSHRL3MBTL1TDP1ESR1LMNA | |
| SCHEMBL27666134 | 0.69 | TSHR (0.53) | TSHRL3MBTL1TDP1ESR1LMNA | |
| SCHEMBL20267305 | 0.69 | TSHR (0.46) | TSHRL3MBTL1TDP1ESR1LMNA | |
| SCHEMBL18154629 | 0.68 | TSHR (0.61) | TSHRL3MBTL1TDP1ESR1LMNA | |
| SCHEMBL136240 | 0.68 | TDP1 (0.56) | TSHRL3MBTL1TDP1ESR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046332-A | New compound | BEECHAM GROUP PLC (GB) | 1990-10-24 | — | — | CN | disclosed |