Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30773357 | 0.86 | LMNA (0.56) | SMN1; SMN2LMNALIPEKDR | |
| SCHEMBL27335162 | 0.86 | LMNA (0.56) | SMN1; SMN2LMNALIPEKDR | |
| SCHEMBL14662134 | 0.86 | PTGER4 (0.51) | MRGPRX4PTGER4THRBNR4A2 | |
| SCHEMBL21628645 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2MRGPRX4PTGER4SCN9ASRD5A2 | |
| SCHEMBL21191142 | 0.82 | TDP1 (0.49) | SMN1; SMN2MRGPRX4PTGER4LMNANR4A2 | |
| SCHEMBL27335800 | 0.79 | HDAC4 (0.44) | SCN9ALMNALIPE | |
| SCHEMBL30773325 | 0.79 | HDAC4 (0.44) | SCN9ALMNALIPE | |
| SCHEMBL27335254 | 0.79 | HDAC4 (0.44) | SCN9ALMNALIPE | |
| SCHEMBL20406363 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNALIPETHRBFFAR1 | |
| SCHEMBL29074786 | 0.78 | SCN9A (0.42) | SMN1; SMN2SCN9ALMNATHRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024003259-A1 | TEAD INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-04 | — | — | WO | disclosed |