Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378165 | 0.79 | GAA (0.49) | GRM2NPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL3058470 | 0.78 | SMN1; SMN2 (0.56) | HTR2CGRM2NPC1RAB9AL3MBTL1 | |
| SCHEMBL30659290 | 0.78 | NPC1 (0.46) | HTR2CNPC1RAB9AL3MBTL1CACNA1G | |
| SCHEMBL3058673 | 0.78 | SMN1; SMN2 (0.56) | HTR2CGRM2NPC1RAB9AL3MBTL1 | |
| SCHEMBL2331248 | 0.78 | KMT2A (0.56) | HTR2CNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL15218647 | 0.77 | SMN1; SMN2 (0.60) | HTR2CNPC1RAB9AL3MBTL1CACNA1G | |
| SCHEMBL14372548 | 0.77 | SMN1; SMN2 (0.60) | HTR2CNPC1RAB9AL3MBTL1CACNA1G | |
| SCHEMBL16472423 | 0.77 | SMN1; SMN2 (0.60) | HTR2CNPC1RAB9AL3MBTL1CACNA1G | |
| SCHEMBL8978249 | 0.77 | HTR2C (0.56) | HTR2CNPC1RAB9AL3MBTL1CACNA1G | |
| SCHEMBL15883699 | 0.76 | SMN1; SMN2 (0.56) | HTR2CNPC1RAB9ACACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1049161-A | Heterogeneous ring compound with serotonine 2-receptor antagonistic activity | DAIICHI SEIYAKU CO (JP) | 1991-02-13 | — | — | CN | disclosed |