Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1929718 | 0.84 | HTR2C (0.48) | HTR2CNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL20701414 | 0.83 | NPC1 (0.51) | HTR2CNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL6173741 | 0.82 | NPC1 (0.50) | HTR2CNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL17481627 | 0.82 | NPC1 (0.50) | HTR2CNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL27526806 | 0.78 | PSEN1 (0.51) | HTR2CBRD4CREBBPPSEN1PSEN2 | |
| SCHEMBL4179954 | 0.77 | HTR2C (0.58) | HTR2CNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL13489645 | 0.77 | HTR2C (0.58) | HTR2CNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL13384650 | 0.77 | HTR2C (0.58) | HTR2CNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL19598727 | 0.77 | HTR2C (0.58) | HTR2CNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL16402949 | 0.77 | PSEN1 (0.50) | HTR2CPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378930-B1 | Cyclic urea derivative | NIPPON PAINT CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5385985-A | Cyclic urea derivative | NIPPON PAINT CO., LTD. (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0378930-A1 | Cyclic urea derivative | NIPPON PAINT CO., LTD. (JP) | 1990-07-25 | — | — | EP | disclosed |