SCHEMBL27337103

SCHEMBL27337103

Cc1cc(C(C)(C)C)c([N+](=O)[O-])c(C)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.51
MEN1 O00255 2/20 0.51
HTT P42858 2/20 0.51
KMT2A Q03164 2/20 0.51
GALR3 O60755 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
ALDH1A1 P00352 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
TSHR P16473 1/20 0.46
GPR35 Q9HC97 3/20 0.42
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
CA2 P00918 2/20 0.38
POLB P06746 1/20 0.38
TYR P14679 1/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4923093 0.85 TSHR (0.51) SMN1; SMN2MEN1HTTKMT2AGALR3
SCHEMBL10411480 0.84 SMN1; SMN2 (0.58) SMN1; SMN2MEN1HTTKMT2AGALR3
SCHEMBL10813783 0.81 TSHR (0.54) SMN1; SMN2MEN1HTTKMT2AGALR3
SCHEMBL28308139 0.80 TSHR (0.49) SMN1; SMN2MEN1HTTKMT2AGALR3
SCHEMBL12406434 0.78 ALDH1A1 (0.42) SMN1; SMN2MEN1HTTKMT2AGALR3
SCHEMBL27322674 0.77 ALDH1A1 (0.63) SMN1; SMN2MEN1HTTKMT2AGALR3
SCHEMBL397236 0.77 SMN1; SMN2 (0.61) SMN1; SMN2MEN1HTTKMT2AGALR3
SCHEMBL19130787 0.75 MEN1 (0.82) SMN1; SMN2MEN1HTTKMT2AGALR3
SCHEMBL11640027 0.75 ALDH1A1 (0.44) MEN1HTTKMT2AL3MBTL1ALDH1A1
SCHEMBL29521866 0.75 ALDH1A1 (0.65) SMN1; SMN2MEN1HTTKMT2AGALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1049124-C Artificial musk serial anti-inflammatory and anticancer compound Chinese patent medicine and making process thereof BEIFANG MEDICINE DEVEL INST ZU (CN) 2000-02-09 CN disclosed