SCHEMBL27337754

SCHEMBL27337754

OCc1nc2ccccc2cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
HPGD P15428 3/20 0.46
MAPT P10636 3/20 0.46
GLA P06280 2/20 0.46
ACHE P22303 1/20 0.46
KMT2A Q03164 4/20 0.46
KDM4E B2RXH2 4/20 0.45
GAA P10253 1/20 0.40
STAT3 P40763 1/20 0.40
MEN1 O00255 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
TLR8 Q9NR97 1/20 0.37
TDP1 Q9NUW8 3/20 0.37
HTR3A P46098 1/20 0.36
IKBKB O14920 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20476289 0.82 KMT2A (0.56) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL1601021 0.81 ALDH1A1 (0.46) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL5197442 0.81 ALDH1A1 (0.46) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL29370497 0.78 ALDH1A1 (0.48) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL8878501 0.78 ALDH1A1 (0.55) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL7927501 0.78 ALDH1A1 (0.48) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL18583409 0.77 ALDH1A1 (0.47) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL1506695 0.77 ALDH1A1 (0.46) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL28237515 0.77 KMT2A (0.42) ALDH1A1HPGDMAPTGLAACHE
Hydrochloric Acid SCHEMBL27548257 0.76 KMT2A (0.39) ALDH1A1HPGDMAPTGLAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1046279-C Quinoline derivative UBE INDUSTRIES (JP) 1999-11-10 CN disclosed