SCHEMBL2733808

SCHEMBL2733808

CCCCCCCCCCCCCCCC[SiH](Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
ALDH1A1 P00352 3/20 0.45
DNM1 Q05193 7/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5843544 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL523165 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6037420 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL8861936 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL17966534 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6037404 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL367261 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL547718 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL3628850 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL117321 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0831112-B1 Sheet and tube organosilicon polymers DOW CORNING (US) 2003-11-26 EP claimed
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 US claimed
EP-0831112-A1 Sheet and tube organosilicon polymers DOW CORNING CORPORATION (US) 1998-03-25 EP claimed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP claimed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 US claimed
CN-111484621-B Polysilosilazane compound, method for preparing the same, composition comprising the same, and cured product thereof 信越化学工业株式会社 2023-06-20 CN disclosed
US-11033507-B2 Method of synthesis of silica vesicles and use thereof THE UNIVERSITY OF QUEENSLAND (AU) 2021-06-15 US disclosed
US-20180193278-A1 METHOD OF SYNTHESIS OF SILICA VESICLES AND USE THEREOF THE UNIVERSITY OF QUEENSLAND (AU) 2018-07-12 US disclosed
CN-102040224-B Hydrophobic core-shell silica particle, hollow silica particle, and manufacturing methods thereof ADEKA CORP 2015-07-15 CN disclosed
CN-102314106-B Method of manufacturing a carrier, a carrier, a development agent, and a process cartridge RICOH CO LTD 2013-05-29 CN disclosed
CN-102193352-B Toner, method of manufacturing toner and image forming method using the toner RICOH CO LTD 2013-04-17 CN disclosed
CN-102314106-A Method of manufacturing a carrier, a carrier, a development agent, and a process cartridge RICOH CO LTD 2012-01-11 CN disclosed
EP-0830410-B1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING & MFG (US) 1999-04-07 EP disclosed
EP-0831112-A1 Sheet and tube organosilicon polymers DOW CORNING CORPORATION (US) 1998-03-25 EP disclosed
EP-0830410-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-25 EP disclosed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP disclosed
US-5654459-A VIA COMPROPORTIONATION OF ALKYLCHLOROSILANES WITH HYDROGENCHLOROSILANES IN THE PRESENCE OF A ZIRCONIUM AND/OR ALUMINUM CATALYST SATURATED WITH A HYDROGEN HALIDE; HIGH YIELD AND PURITY HUELS AKTIENGESELLSCHAFT (DE) 1997-08-05 US disclosed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 US disclosed
WO-1996039457-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-12 WO disclosed
EP-0747384-A1 Process for the preparation of alkylhydrogenchlorosilanes HÜLS AKTIENGESELLSCHAFT (DE) 1996-12-11 EP disclosed