SCHEMBL367261

SCHEMBL367261

CCCCCCCCCCCCC[SiH](Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
ALDH1A1 P00352 3/20 0.45
DNM1 Q05193 7/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5843544 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL523165 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6037420 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL8861936 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL17966534 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6037404 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL547718 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL2733808 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL3628850 1.00 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL117321 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114316452-A Super-hydrophobic foamed polypropylene and preparation method thereof 苏州浩纳新材料科技有限公司 2022-04-12 CN claimed
EP-3307816-A1 HIGH STRENGTH AND MOISTURE RESISTANT ADHESIVE Bison International B.v. (NL) 2018-04-18 EP claimed
WO-2016202359-A1 HIGH STRENGTH AND MOISTURE RESISTANT ADHESIVE BISON INTERNATIONAL B.V. (NL) 2016-12-22 WO claimed
WO-2014170799-A1 CROSSLINKABLE VARNISH AND METHOD FOR APPLYING SAME COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-10-23 WO claimed
EP-1546267-B1 HYDROPHOBING SILICA WITH ORGANOSILICON COMPOUNDS AND BLENDS THEREOF DOW CORNING (US) 2006-05-31 EP claimed
EP-1546267-A2 HYDROPHOBING SILICA WITH ORGANOSILICON COMPOUNDS AND BLENDS THEREOF Dow Corning Corporation (US) 2005-06-29 EP claimed
US-20040227127-A1 Hydrophobing silica with organosilicon compounds and blends thereof BOSWELL LISA MARIE (US) 2004-11-18 US claimed
US-6811823-B2 CONTACTING SILICA SURFACES WITH DIALKYLDICHLOROSILANES AND TRIALKOXYSILANES THAT ARE FREE OF REACTIVE HYDROCARBON OF ORGANOFUNCTIONAL GROUPS; RUBBER TIRES DOW CORNING CORPORATION 2004-11-02 US claimed
WO-2004024831-A2 HYDROPHOBING SILICA WITH ORGANOSILICON COMPOUNDS AND BLENDS THEREOF DOW CORNING CORPORATION (US) 2004-03-25 WO claimed
US-20040052939-A1 Hydrophobing silica with organosilicon compounds and blends thereof DOW CORNING CORPORATION 2004-03-18 US claimed
CN-119080823-A Method for preparing tetramethylsilane and active siloxane by using low-boiling-point substances 郭兰 2024-12-06 CN disclosed
EP-3743464-B1 ORGANIC-INORGANIC AEROGEL COMPOSITES, METHODS AND USES THEREOF BRONX CREATIVE&DESIGN CENTRE PTE LTD (SG) 2024-03-06 EP disclosed
CN-110660761-B Heat-conducting structure or semiconductor device 丰田自动车株式会社 2023-10-20 CN disclosed
US-11739184-B2 Polysiloxazane compound having alkoxysilyl group, process for producing same, and composition and cured product including same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-29 US disclosed
US-20230250250-A1 Organic-inorganic Aerogel Composites, Methods and Uses Thereof BRONX CREATIVE & DESIGN CENTRE PTE LTD (SG) 2023-08-10 US disclosed
US-4758637-A Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom UNION CARBIDE CORPORATION (US) 1988-07-19 US disclosed
EP-0269023-A2 Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom UNION CARBIDE CORPORATION (US) 1988-06-01 EP disclosed
EP-0214658-A2 Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom UNION CARBIDE CORPORATION (US) 1987-03-18 EP disclosed
US-4640962-A Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom UNION CARBIDE CORPORATION (US) 1987-02-03 US disclosed
US-4374178-A PRETREATED WITH SODIUM SILICATE UNION CARBIDE CORPORATION (US) 1983-02-15 US disclosed