⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701185 | 0.79 | HTR3A (0.34) | — | |
| SCHEMBL27964810 | 0.78 | AKR1B1 (0.36) | — | |
| SCHEMBL27756127 | 0.76 | KDM4E (0.33) | — | |
| SCHEMBL27328289 | 0.76 | DAO (0.35) | — | |
| SCHEMBL27333181 | 0.76 | KDM4E (0.33) | — | |
| SCHEMBL27663613 | 0.70 | CYP19A1 (0.38) | — | |
| SCHEMBL27711035 | 0.70 | BRD4 (0.38) | — | |
| SCHEMBL27482997 | 0.70 | CYP3A4 (0.37) | — | |
| SCHEMBL27668220 | 0.70 | CHEK1 (0.39) | — | |
| SCHEMBL27328163 | 0.68 | GAA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290359-A | Preparation method of 6-amino-7-fluoro-4-propynyl-1, 4-benzoxazine-3- (4H) ketone | 山东京博农化科技股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118146172-A | Preparation method of 7-fluoro-6-amino-2H-1, 4-benzoxazine-3 (4H) -one | 帕潘纳(北京)科技有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-117263880-A | Synthesis method of 6-amino-7-fluoro-2H-benzo [ b ] [1,4] oxazine-3 (4H) -ketone | 山东友聚医药科技有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-117164576-A | Synthesis method of flumioxazin | 上海农帆生物科技有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-113912561-B | Synthetic method of 6-amino-7-fluoro-2H-1, 4-benzoxazine-3 (4H) -ketone | 山东京博农化科技股份有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115466249-A | Preparation method of flumioxazin | 上海农帆生物科技有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-113912561-A | Synthetic method of 6-amino-7-fluoro-2H-1, 4-benzoxazine-3 (4H) -ketone | 京博农化科技有限公司 | 2022-01-11 | — | — | CN | claimed |
| CN-113045557-A | Production process of flumioxazin herbicide | 宁夏一帆生物科技有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-110655513-A | Synthetic method of flumioxazin | 浙江南郊化学有限公司 | 2020-01-07 | — | — | CN | claimed |
| CN-110627738-A | Synthetic method of pesticide intermediate for synthesizing flumioxazin | 浙江南郊化学有限公司 | 2019-12-31 | — | — | CN | claimed |
| CN-118324708-A | Synthesis method of flumioxazin intermediate 6-amino-7-fluoro-2H-benzo [ b ] [1,4] oxazin-3 (4H) -ketone | 山东滨农科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118324708-A | Synthesis method of flumioxazin intermediate 6-amino-7-fluoro-2H-benzo [ b ] [1,4] oxazin-3 (4H) -ketone | 山东滨农科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118290359-A | Preparation method of 6-amino-7-fluoro-4-propynyl-1, 4-benzoxazine-3- (4H) ketone | 山东京博农化科技股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118290359-A | Preparation method of 6-amino-7-fluoro-4-propynyl-1, 4-benzoxazine-3- (4H) ketone | 山东京博农化科技股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118146172-A | Preparation method of 7-fluoro-6-amino-2H-1, 4-benzoxazine-3 (4H) -one | 帕潘纳(北京)科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-113045557-A | Production process of flumioxazin herbicide | 宁夏一帆生物科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-110655513-A | Synthetic method of flumioxazin | 浙江南郊化学有限公司 | 2020-01-07 | — | — | CN | disclosed |
| CN-110627738-A | Synthetic method of pesticide intermediate for synthesizing flumioxazin | 浙江南郊化学有限公司 | 2019-12-31 | — | — | CN | disclosed |
| CN-103965181-A | Preparation method of flumioxazin | UNIV HEILONGJIANG | 2014-08-06 | — | — | CN | disclosed |
| CN-1049770-A | Weeding glutaramic acid and its derivative | ROHM & HAAS (US) | 1991-03-13 | — | — | CN | disclosed |