Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 6/20 | 0.41 |
| ▸ | TNNI3K | Q59H18 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27323499 | 0.82 | MEN1 (0.51) | EGFRTNNI3KMEN1KMT2ANPC1 | |
| SCHEMBL27339277 | 0.82 | EGFR (0.45) | EGFRTNNI3KMEN1KMT2ANPC1 | |
| SCHEMBL27330845 | 0.82 | TNNI3K (0.54) | EGFRTNNI3KERBB3AURKA | |
| SCHEMBL27334593 | 0.78 | EGFR (0.41) | DPP4EGFRTNNI3KMEN1KMT2A | |
| SCHEMBL27408587 | 0.78 | EGFR (0.58) | PRCPEGFRTNNI3KMEN1KMT2A | |
| SCHEMBL27318731 | 0.78 | EGFR (0.47) | EGFRTNNI3KMEN1KMT2ANPC1 | |
| SCHEMBL27345375 | 0.78 | MEN1 (0.69) | EGFRTNNI3KMEN1KMT2ANPC1 | |
| SCHEMBL27320738 | 0.78 | KDM1A (0.48) | EGFRPRKCICYP1A2 | |
| SCHEMBL27337230 | 0.78 | FLT3 (0.45) | EGFRTNNI3KMEN1KMT2ANPC1 | |
| SCHEMBL8798647 | 0.76 | EGFR (0.55) | EGFRTNNI3KMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1047778-C | Pyrimido [5-4-d] pyrimidines, drugs containing these compounds, their use and process for preparing them | THOMAE GMBH DR K (DE) | 1999-12-29 | — | — | CN | disclosed |