Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 4/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 7/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704689 | 0.91 | NR1H4 (0.49) | EPHA2NR1H4ERBB2EPHB4DRD4 | |
| SCHEMBL8702864 | 0.91 | NR1H4 (0.49) | EPHA2NR1H4ERBB2EPHB4DRD4 | |
| SCHEMBL8702860 | 0.91 | NR1H4 (0.49) | EPHA2NR1H4ERBB2EPHB4DRD4 | |
| SCHEMBL8702892 | 0.89 | EPHA2 (0.49) | EPHA2NR1H4ERBB2EPHB4 | |
| SCHEMBL8707388 | 0.89 | EPHA2 (0.49) | EPHA2NR1H4ERBB2EPHB4 | |
| SCHEMBL8703515 | 0.89 | EPHA2 (0.49) | EPHA2NR1H4ERBB2EPHB4 | |
| SCHEMBL8706383 | 0.88 | NR1H4 (0.48) | EPHA2NR1H4ERBB2EPHB4DRD4 | |
| SCHEMBL28851224 | 0.86 | EPHA2 (0.51) | EPHA2NR1H4ERBB2EPHB4DRD4 | |
| SCHEMBL13482008 | 0.85 | EPHA2 (0.51) | EPHA2NR1H4ERBB2EPHB4DRD4 | |
| SCHEMBL4510923 | 0.84 | EPHA2 (0.54) | EPHA2NR1H4ERBB2EPHB4DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1044365-C | Alpha, omega-diarylalkane derivatives, their preparation and their use in the treatment and prevention of circulatory diseases and psychosis | SANKYO CO (JP) | 1999-07-28 | — | — | CN | disclosed |