Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A11 | Q9UPY5 | 5/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27338041 | 0.86 | SLC7A11 (0.54) | SLC7A11MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL27341664 | 0.86 | SLC7A11 (0.56) | SLC7A11PTPN11MEN1KMT2AMAPK1 | |
| SCHEMBL8067735 | 0.81 | SLC7A11 (0.79) | SLC7A11MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL27525188 | 0.79 | SLC7A11 (0.54) | SLC7A11PTPN11KMT2AALDH1A1MAPK1 | |
| SCHEMBL27343979 | 0.77 | SLC7A11 (0.49) | SLC7A11MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL27345098 | 0.73 | PTGS2 (0.47) | SLC7A11MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL27331598 | 0.72 | SLC7A11 (0.48) | SLC7A11KMT2AALDH1A1MAPK1MAPT | |
| SCHEMBL8067223 | 0.70 | SLC7A11 (0.81) | SLC7A11PTPN11MEN1KMT2AALDH1A1 | |
| SCHEMBL8067733 | 0.70 | SLC7A11 (1.00) | SLC7A11MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL27343982 | 0.69 | SLC7A11 (0.42) | SLC7A11ALDH1A1MAPK1MAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1042631-C | Novel substituted salicylic acids | KABI PHARMACIA AB (SE) | 1999-03-24 | — | — | CN | disclosed |
| CN-1088918-A | The salicylic acid compounds of new replacement | KABI PHARMACIA AB (SE) | 1994-07-06 | — | — | CN | disclosed |