SCHEMBL27341237

SCHEMBL27341237

C=C(C)C(CC(C)=N)Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
CPA1 P15085 4/20 0.44
CPA3 P15088 3/20 0.44
CPB1 P15086 1/20 0.44
CPB2 Q96IY4 1/20 0.44
FOLH1 Q04609 1/20 0.41
MME P08473 1/20 0.39
ALPI P09923 1/20 0.39
PKM P14618 1/20 0.39
PTGS1 P23219 1/20 0.39
XIAP P98170 1/20 0.39
SLC7A5 Q01650 1/20 0.39
TRPA1 O75762 1/20 0.39
LTA4H P09960 2/20 0.39
SLC6A2 P23975 2/20 0.38
TAAR1 Q96RJ0 2/20 0.38
MAOA P21397 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
SIGMAR1 Q99720 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6684404 0.82 CPA1 (0.68) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL29197871 0.79 CYP1A2 (0.55) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL24439255 0.74 CYP1A2 (0.44) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL20262939 0.72 MDM2 (0.50) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL18034348 0.72 EPHX1 (0.52) CYP1A2CPA3ALPIPKMPTGS1
SCHEMBL6161602 0.72 CYP1A2 (0.60) CYP1A2CPA1CPA3CPB1CPB2
SCHEMBL13622891 0.71 TAAR1 (0.50) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL21417480 0.71 ALPI (0.61) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL21953436 0.71 TRPA1 (0.47) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL8325402 0.71 ALPI (0.61) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023235384-A1 COMPOUNDS FOR ENHANCING READ THROUGH OF GENES CONTAINING PREMATURE TERMINATION CODONS AND METHODS FOR MAKING AND USING THE SAME SANOFI US SERVICES INC. (US) 2023-12-07 WO disclosed