Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31034749 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1HPGDPOLBXBP1 | |
| SCHEMBL27342240 | 0.91 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDPOLBXBP1 | |
| SCHEMBL27342246 | 0.90 | KDM4E (0.55) | KDM4EALDH1A1HPGDPOLBXBP1 | |
| SCHEMBL27341331 | 0.90 | KMT2A (0.56) | KDM4EALDH1A1HPGDPOLBXBP1 | |
| SCHEMBL27341472 | 0.90 | KMT2A (0.56) | KDM4EALDH1A1HPGDPOLBXBP1 | |
| SCHEMBL27341196 | 0.90 | KMT2A (0.56) | KDM4EALDH1A1HPGDPOLBXBP1 | |
| SCHEMBL31065369 | 0.90 | KMT2A (0.56) | KDM4EALDH1A1HPGDPOLBXBP1 | |
| SCHEMBL27341859 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1HPGDPOLBXBP1 | |
| SCHEMBL27342242 | 0.87 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDPOLBXBP1 | |
| SCHEMBL27341857 | 0.87 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDPOLBXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |