⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596437 | 1.00 | — | — | |
| SCHEMBL4591064 | 0.69 | — | — | |
| SCHEMBL6596432 | 0.68 | — | — | |
| SCHEMBL3429894 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL29288170 | 0.64 | — | — | |
| SCHEMBL94647 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL11727781 | 0.62 | — | — | |
| SCHEMBL10643192 | 0.62 | — | — | |
| SCHEMBL8035040 | 0.61 | KMT2A (0.37) | — | |
| SCHEMBL3618802 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060472-C | Tricyclic substituted hydroxamic acid derivatives, process for their preparation, medicaments containing them and their use | HOFFMANN LA ROCHE (CH) | 2001-01-10 | — | — | CN | claimed |
| CN-1129216-A | Tricyclic Substituted Hydroxamic Acid Derivatives | HOFFMANN LA ROCHE (CH) | 1996-08-21 | — | — | CN | claimed |
| CN-1095835-C | Derivatives of tricyclo-substituted isohydroxyloxime acid | HOFFMANN LA ROCHE (CH) | 2002-12-11 | — | — | CN | disclosed |
| CN-1340050-A | Heterocyclic benzenesulphonamide compounds as bradykinine antagonists | FOURNIER IND & SANTE (FR) | 2002-03-13 | — | — | CN | disclosed |
| CN-1310629-A | Combined administration of ACAT and MMP inhibitors for the treatment of atherosclerotic lesions | WARNER LAMBERT CO (US) | 2001-08-29 | — | — | CN | disclosed |
| CN-1060472-C | Tricyclic substituted hydroxamic acid derivatives, process for their preparation, medicaments containing them and their use | HOFFMANN LA ROCHE (CH) | 2001-01-10 | — | — | CN | disclosed |
| CN-1270166-A | Derivatives of tricyclo-substituted isohydroxyloxime acid | HOFFMANN LA ROCHE (CH) | 2000-10-18 | — | — | CN | disclosed |
| CN-1129216-A | Tricyclic Substituted Hydroxamic Acid Derivatives | HOFFMANN LA ROCHE (CH) | 1996-08-21 | — | — | CN | disclosed |