SCHEMBL8035040

SCHEMBL8035040

O=C(NC1NCCS1)C(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3429894 0.79
SCHEMBL28334263 0.75
SCHEMBL9814349 0.71 MAPT (0.32)
SCHEMBL7248025 0.67 NFKB1 (0.39) KMT2A
SCHEMBL4443315 0.66
SCHEMBL3181606 0.65 MEN1 (0.31) KMT2A
SCHEMBL27973387 0.63
SCHEMBL8355774 0.63 KMT2A (0.37) KMT2A
SCHEMBL28399016 0.62 KMT2A (0.36) KMT2A
SCHEMBL23421623 0.62 MAPT (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994026108-A1 SAFENING PYRIDYLOXYPHENOXY PROPIONIC ACID HERBICIDES ZENECA LIMITED (GB) 1994-11-24 WO claimed
EP-0802732-B1 HERBICIDAL COMPOSITIONS OF 4-BENZOYLISOXAZOLE OR 2-CYANO-1,3-DIONE HERBICIDES AND ANTIDOTES THEREFOR ZENECA LTD (GB) 2000-04-19 EP disclosed
WO-2000011954-A1 HERBICIDAL METHOD AVENTIS CROPSCIENCE S.A. (FR) 2000-03-09 WO disclosed
EP-0802732-A1 HERBICIDAL COMPOSITIONS OF 4-BENZOYLISOXAZOLE OR 2-CYANO-1,3-DIONE HERBICIDES AND ANTIDOTES THEREFOR ZENECA LIMITED (GB) 1997-10-29 EP disclosed
US-5627131-A Herbicidal compositions of 4-benzoylisoxazole and antidotes therefor ZENECA LIMITED (GB) 1997-05-06 US disclosed
WO-1996021357-A1 HERBICIDAL COMPOSITIONS OF 4-BENZOYLISOXAZOLE OR 2-CYANO-1,3-DIONE HERBICIDES AND ANTIDOTES THEREFOR ZENECA LIMITED (GB) 1996-07-18 WO disclosed