Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344137 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBHPGDNPSR1 | |
| SCHEMBL27344138 | 0.92 | KDM4E (0.52) | ALDH1A1KDM4EPOLBHPGDNPSR1 | |
| SCHEMBL27344630 | 0.92 | KDM4E (0.50) | ALDH1A1KDM4EPOLBHPGDNPSR1 | |
| SCHEMBL27344134 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KDM4EPOLBHPGDNPSR1 | |
| SCHEMBL27344226 | 0.90 | ALDH1A1 (0.47) | ALDH1A1KDM4EPOLBHPGDNPSR1 | |
| SCHEMBL27344632 | 0.88 | KDM4E (0.48) | ALDH1A1KDM4EPOLBHPGDNPSR1 | |
| SCHEMBL31065369 | 0.87 | KMT2A (0.56) | ALDH1A1KDM4EPOLBHPGDNPSR1 | |
| SCHEMBL27341331 | 0.87 | KMT2A (0.56) | ALDH1A1KDM4EPOLBHPGDNPSR1 | |
| SCHEMBL27341472 | 0.87 | KMT2A (0.56) | ALDH1A1KDM4EPOLBHPGDNPSR1 | |
| SCHEMBL27341196 | 0.87 | KMT2A (0.56) | ALDH1A1KDM4EPOLBHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |