Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10343728 | 0.80 | CYP4F2 (0.39) | LMNACYP4F2CYP4A11NPSR1MAPT | |
| SCHEMBL1066549 | 0.80 | PLG (0.44) | PLGPLATLMNACYP2D6KCNH2 | |
| SCHEMBL15115984 | 0.80 | CYP4F2 (0.39) | LMNACYP4F2CYP4A11NPSR1MAPT | |
| SCHEMBL10326319 | 0.80 | CYP4F2 (0.39) | LMNACYP4F2CYP4A11NPSR1MAPT | |
| SCHEMBL2285823 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL15227957 | 0.79 | PLG (0.42) | PLGPLATLMNACYP2D6KCNH2 | |
| SCHEMBL15534962 | 0.79 | PLG (0.38) | PLGPLATLMNACYP4F2CYP4A11 | |
| SCHEMBL16886412 | 0.77 | CYP4F2 (0.37) | CYP4F2CYP4A11NPSR1MAPT | |
| SCHEMBL28563596 | 0.77 | CYP4F2 (0.37) | PLGPLATLMNACYP4F2CYP4A11 | |
| SCHEMBL16875398 | 0.77 | GAA (0.41) | CYP4F2CYP4A11NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024127297-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | PFIZER INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024075051-A1 | HSD17B13 INHIBITORS AND/OR DEGRADERS | PFIZER INC. (US) | 2024-04-11 | — | — | WO | disclosed |