Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14380147 | 0.83 | FFAR3 (0.33) | LMNANPSR1FFAR3MAPTCYP4F2 | |
| SCHEMBL9044471 | 0.83 | CYP4F2 (0.35) | LMNANPSR1FFAR3MAPTCYP4F2 | |
| SCHEMBL31200302 | 0.81 | NPSR1 (0.32) | NPSR1FFAR3MAPTCYP4F2CYP4A11 | |
| SCHEMBL17317622 | 0.80 | FFAR4 (0.39) | FFAR3 | |
| SCHEMBL27344356 | 0.79 | PLG (0.36) | PLGPLATLMNACYP2D6KCNH2 | |
| SCHEMBL483341 | 0.79 | PLG (0.36) | PLGPLATLMNACYP2D6KCNH2 | |
| SCHEMBL9043242 | 0.79 | FFAR3 (0.36) | LMNANPSR1FFAR3MAPT | |
| SCHEMBL13240708 | 0.79 | FFAR3 (0.36) | LMNANPSR1FFAR3MAPT | |
| SCHEMBL13240707 | 0.79 | FFAR3 (0.36) | LMNANPSR1FFAR3MAPT | |
| Hydrochloric Acid SCHEMBL1543212 | 0.77 | FFAR3 (0.34) | LMNANPSR1FFAR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019063748-A1 | ROR-GAMMA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-04-04 | — | — | WO | disclosed |
| WO-2019063748-A1 | ROR-GAMMA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-04-04 | — | — | WO | disclosed |
| WO-2013177349-A2 | QUINAZOLINEDIONES AS TANKYRASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-11-28 | — | — | WO | disclosed |