Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYBB | P04839 | 1/20 | 0.33 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31512648 | 0.94 | ACE2 (0.49) | ACE2ALOX5JUNNFKB1NFKB2 | |
| SCHEMBL31512645 | 0.93 | ACE2 (0.40) | ACE2ALOX5JUNNFKB1NFKB2 | |
| SCHEMBL18448706 | 0.82 | ACE2 (0.45) | ACE2ALOX5JUNNFKB1NFKB2 | |
| SCHEMBL31512628 | 0.78 | ACE2 (0.44) | ACE2ALOX5JUNNFKB1NFKB2 | |
| SCHEMBL27344284 | 0.78 | ACE2 (0.49) | ACE2ALOX5JUNNFKB1NFKB2 | |
| SCHEMBL30811571 | 0.78 | ACE2 (0.49) | ACE2ALOX5JUNNFKB1NFKB2 | |
| SCHEMBL27344609 | 0.78 | ACE2 (0.46) | ACE2ALOX5JUNNFKB1NFKB2 | |
| SCHEMBL27344608 | 0.78 | ACE2 (0.46) | ACE2ALOX5JUNNFKB1NFKB2 | |
| SCHEMBL27344606 | 0.78 | ACE2 (0.46) | ACE2ALOX5JUNNFKB1NFKB2 | |
| SCHEMBL27344291 | 0.78 | ACE2 (0.49) | ACE2ALOX5JUNNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |