Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.35 |
| ▸ | CYBB | P04839 | 1/20 | 0.35 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.35 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18448706 | 0.85 | ACE2 (0.45) | ACE2JUNNFKB1NFKB2RELA | |
| SCHEMBL30811571 | 0.82 | ACE2 (0.49) | ACE2JUNNFKB1NFKB2RELA | |
| SCHEMBL27344291 | 0.82 | ACE2 (0.49) | ACE2JUNNFKB1NFKB2RELA | |
| SCHEMBL27344606 | 0.82 | ACE2 (0.46) | ACE2JUNNFKB1NFKB2RELA | |
| SCHEMBL27344608 | 0.82 | ACE2 (0.46) | ACE2JUNNFKB1NFKB2RELA | |
| SCHEMBL27344284 | 0.82 | ACE2 (0.49) | ACE2JUNNFKB1NFKB2RELA | |
| SCHEMBL29636446 | 0.81 | ALOX5 (0.59) | ACE2ALOX5NOX1CYBBNOX3 | |
| SCHEMBL18614108 | 0.81 | ALOX5 (0.59) | ACE2ALOX5NOX1CYBBNOX3 | |
| SCHEMBL27344607 | 0.78 | ACE2 (0.43) | ACE2JUNNFKB1NFKB2RELA | |
| SCHEMBL27344515 | 0.78 | ACE2 (0.49) | ACE2JUNNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |