Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | EBP | Q15125 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719479 | 1.00 | DHCR7 (0.65) | DHCR7MEN1KMT2AHTTCYP2D6 | |
| SCHEMBL27344746 | 1.00 | DHCR7 (0.65) | DHCR7MEN1KMT2AHTTCYP2D6 | |
| SCHEMBL17007486 | 0.87 | DHCR7 (0.80) | DHCR7MEN1KMT2AHTTCYP2D6 | |
| Hydrochloric Acid SCHEMBL17007507 | 0.86 | DHCR7 (0.78) | DHCR7MEN1KMT2AHTTCYP2D6 | |
| SCHEMBL25315710 | 0.86 | DHCR7 (0.61) | DHCR7MEN1KMT2AHTTCYP2D6 | |
| SCHEMBL25315405 | 0.86 | DHCR7 (0.61) | DHCR7MEN1KMT2AHTTCYP2D6 | |
| SCHEMBL25429083 | 0.86 | DHCR7 (0.61) | DHCR7MEN1KMT2AHTTCYP2D6 | |
| SCHEMBL25429080 | 0.86 | DHCR7 (0.61) | DHCR7MEN1KMT2AHTTCYP2D6 | |
| SCHEMBL25315410 | 0.86 | DHCR7 (0.61) | DHCR7MEN1KMT2AHTTCYP2D6 | |
| SCHEMBL25316374 | 0.86 | DHCR7 (0.61) | DHCR7MEN1KMT2AHTTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015503-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |