Sugi Predict

Sugi Predict / Compounds / SCHEMBL25315410

SCHEMBL25315410

SCHEMBL25315410

CC1CCN(C2C[C@H]3CC[C@@H](C2)N3S(=O)(=O)c2ccc(OC(F)F)cc2)CC1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DHCR7 Q9UBM7 2/20 0.61
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ HTT P42858 2/20 0.44
▸ CYP2D6 P10635 2/20 0.44
▸ EBP Q15125 1/20 0.44
▸ MCOLN3 Q8TDD5 1/20 0.43
▸ PTGDR2 Q9Y5Y4 1/20 0.42
▸ LMNA P02545 3/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ RECQL P46063 1/20 0.40
▸ DRD2 P14416 1/20 0.40
▸ ADRA1D P25100 1/20 0.40
▸ ADRA1A P35348 1/20 0.40
▸ ADRA1B P35368 1/20 0.40
▸ HSD11B1 P28845 2/20 0.40
▸ KDM2B Q8NHM5 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25429083 1.00 DHCR7 (0.61) DHCR7MEN1KMT2AHTTCYP2D6
SCHEMBL25316374 1.00 DHCR7 (0.61) DHCR7MEN1KMT2AHTTCYP2D6
SCHEMBL25315710 1.00 DHCR7 (0.61) DHCR7MEN1KMT2AHTTCYP2D6
SCHEMBL25315405 1.00 DHCR7 (0.61) DHCR7MEN1KMT2AHTTCYP2D6
SCHEMBL25429080 1.00 DHCR7 (0.61) DHCR7MEN1KMT2AHTTCYP2D6
SCHEMBL27344746 0.86 DHCR7 (0.65) DHCR7MEN1KMT2AHTTCYP2D6
SCHEMBL27344646 0.86 DHCR7 (0.65) DHCR7MEN1KMT2AHTTCYP2D6
SCHEMBL30719479 0.86 DHCR7 (0.65) DHCR7MEN1KMT2AHTTCYP2D6
SCHEMBL17007486 0.84 DHCR7 (0.80) DHCR7MEN1KMT2AHTTCYP2D6
SCHEMBL25315350 0.84 HSD11B1 (0.47) DHCR7CYP2D6PTGDR2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161281-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-22 — — US claimed
CN-119095845-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2024-12-06 — — CN claimed
EP-4469155-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2024-12-04 — — EP claimed
WO-2023141323-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-07-27 — — WO claimed
US-20250161281-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-22 — — US disclosed
CN-119095845-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2024-12-06 — — CN disclosed
EP-4469155-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2024-12-04 — — EP disclosed
WO-2023141323-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-07-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161281-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF EBPL, EBP, CREBBP DHCR7 2873/4885MEN1 4004/4885KMT2A 3848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.