Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30811606 | 1.00 | PDE3B (0.52) | PDE3BPDE3AALDH1A1MEN1KMT2A | |
| SCHEMBL27344794 | 0.88 | PDE3B (0.50) | PDE3BPDE3AALDH1A1MEN1KMT2A | |
| SCHEMBL30811542 | 0.88 | PDE3B (0.50) | PDE3BPDE3AALDH1A1MEN1KMT2A | |
| SCHEMBL27344603 | 0.85 | PDE3B (0.56) | PDE3BPDE3AALDH1A1MEN1KMT2A | |
| SCHEMBL27346280 | 0.81 | ALOX5 (0.34) | PDE3BPDE3AALDH1A1MEN1KMT2A | |
| SCHEMBL27346252 | 0.80 | PDE3B (0.55) | PDE3BPDE3AALDH1A1MEN1KMT2A | |
| SCHEMBL27344784 | 0.80 | PDE3B (0.55) | PDE3BPDE3AALDH1A1MEN1KMT2A | |
| SCHEMBL30811582 | 0.80 | PDE3B (0.55) | PDE3BPDE3AALDH1A1MEN1KMT2A | |
| SCHEMBL30811584 | 0.79 | PDE3B (0.55) | PDE3BPDE3AALDH1A1MEN1KMT2A | |
| SCHEMBL27346243 | 0.79 | PDE3B (0.55) | PDE3BPDE3AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |