Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27345174 | 1.00 | KDM4E (0.43) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL24207467 | 1.00 | KDM4E (0.43) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL21876917 | 0.93 | BRD4 (0.42) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31312877 | 0.91 | KMT2A (0.39) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL24421386 | 0.91 | KMT2A (0.39) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL25370050 | 0.86 | PTPN1 (0.41) | USP30NOTUMBRD4 | |
| SCHEMBL25370055 | 0.86 | PTPN1 (0.41) | USP30NOTUMBRD4 | |
| SCHEMBL26969667 | 0.86 | PTPN1 (0.41) | USP30NOTUMBRD4 | |
| SCHEMBL29614639 | 0.84 | BRD4 (0.44) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL24421376 | 0.84 | BRD4 (0.44) | KDM4EMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245150-A1 | KAT6 TARGETING COMPOUNDS WITH UBIQUITIN LIGASE BINDING MOIETY | PRELUDE THERAPEUTICS INCORPORATED (US) | 2023-12-21 | — | — | WO | disclosed |