Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24421376 | 1.00 | BRD4 (0.44) | BRD4ALDH1A1SIRT6HTR6LRRK2 | |
| SCHEMBL21876917 | 0.91 | BRD4 (0.42) | BRD4ALDH1A1SIRT6HTR6LRRK2 | |
| SCHEMBL27345173 | 0.84 | KDM4E (0.43) | BRD4ALDH1A1SIRT6HTR6KMT2A | |
| SCHEMBL24207467 | 0.84 | KDM4E (0.43) | BRD4ALDH1A1SIRT6HTR6KMT2A | |
| SCHEMBL27345174 | 0.84 | KDM4E (0.43) | BRD4ALDH1A1SIRT6HTR6KMT2A | |
| SCHEMBL26648895 | 0.82 | ALDH1A1 (0.42) | ALDH1A1SIRT6HTR6KMT2AMEN1 | |
| SCHEMBL27239095 | 0.81 | USP30 (0.48) | ALDH1A1SIRT6HTR6LRRK2KMT2A | |
| SCHEMBL26649385 | 0.80 | CHRM4 (0.44) | ALDH1A1SIRT6HTR6LRRK2KMT2A | |
| SCHEMBL24421198 | 0.79 | FFAR4 (0.39) | ALDH1A1KMT2AMEN1KDM4ENPC1 | |
| SCHEMBL24421386 | 0.78 | KMT2A (0.39) | ALDH1A1SIRT6HTR6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240743-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Prelude Therapeutics, Incorporated (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099117-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | PRELUDE THERAPEUTICS INCORPORATED (US) | 2022-05-12 | — | — | WO | disclosed |