Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.39 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647935 | 0.82 | NPSR1 (0.37) | MAPTKMT2ANPSR1MEN1LMNA | |
| SCHEMBL8622781 | 0.75 | KMT2A (0.43) | MAPTKMT2ANPSR1MEN1LMNA | |
| SCHEMBL10656978 | 0.73 | KMT2A (0.42) | MAPTKMT2ANPSR1MEN1LMNA | |
| SCHEMBL8625478 | 0.72 | KMT2A (0.41) | MAPTKMT2ANPSR1MEN1LMNA | |
| SCHEMBL116506 | 0.72 | KMT2A (0.40) | MAPTKMT2ANPSR1MEN1LMNA | |
| SCHEMBL1476620 | 0.72 | KMT2A (0.40) | MAPTKMT2ANPSR1MEN1LMNA | |
| SCHEMBL1476623 | 0.72 | KMT2A (0.40) | MAPTKMT2ANPSR1MEN1LMNA | |
| SCHEMBL8625558 | 0.72 | KMT2A (0.40) | MAPTKMT2ANPSR1MEN1LMNA | |
| SCHEMBL27740998 | 0.71 | TSHR (0.49) | MAPTKMT2ANPSR1MEN1LMNA | |
| SCHEMBL6651194 | 0.71 | MAPT (0.39) | MAPTKMT2ANPSR1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1042936-C | Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-hiv agent | UBE INDUSTRIES (JP) | 1999-04-14 | — | — | CN | disclosed |
| CN-1086515-A | Aminoquinolone derivative and anti-hiv agent that aryl or fragrant heterocyclic radical replace | UBE INDUSTRIES (JP) | 1994-05-11 | — | — | CN | disclosed |