Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.43 |
| ▸ | TDO2 | P48775 | 8/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 3/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27280965 | 0.75 | IDO1 (0.46) | IDO1TDO2DPP4TSHRF2 | |
| SCHEMBL127629 | 0.75 | IDO1 (0.46) | IDO1TDO2DPP4TSHRF2 | |
| SCHEMBL3889250 | 0.74 | IDO1 (0.41) | IDO1TDO2DPP4TSHRF2 | |
| Ammonia Solution, Strong SCHEMBL7282272 | 0.73 | IDO1 (0.44) | IDO1TDO2DPP4TSHRF2 | |
| Water SCHEMBL11878861 | 0.73 | IDO1 (0.44) | IDO1TDO2DPP4TSHRF2 | |
| Methane SCHEMBL29089947 | 0.73 | IDO1 (0.44) | IDO1TDO2DPP4TSHRF2 | |
| SCHEMBL461447 | 0.71 | IDO1 (0.43) | IDO1TDO2DPP4TSHRF2 | |
| SCHEMBL530933 | 0.71 | IDO1 (0.43) | IDO1TDO2DPP4TSHRF2 | |
| SCHEMBL675765 | 0.71 | IDO1 (0.43) | IDO1TDO2DPP4TSHRF2 | |
| SCHEMBL9315772 | 0.71 | IDO1 (0.48) | IDO1TDO2DPP4TSHRF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632912-A2 | ANTI-CANCER SERINE HYDROLASE INHIBITORY CARBAMATES | The Scripps Research Institute (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012058115-A2 | ANTI-CANCER SERINE HYDROLASE INHIBITORY CARBAMATES | CRAVATT BENJAMIN (US) | 2012-05-03 | — | — | WO | disclosed |