Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1516719 | 0.90 | EGFR (0.48) | EGFRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL27345687 | 0.89 | MRGPRX4 (0.52) | EGFRNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL27345601 | 0.89 | EGFR (0.48) | EGFRHPGDALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15884409 | 0.88 | EGFR (0.52) | EGFRNPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL17129014 | 0.86 | EGFR (0.47) | EGFRNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL25179630 | 0.86 | DGAT1 (0.46) | EGFRNPC1RAB9ACSF1RHIF1A | |
| SCHEMBL29362049 | 0.86 | DGAT1 (0.46) | EGFRNPC1RAB9ACSF1RHIF1A | |
| SCHEMBL31034717 | 0.85 | EGFR (0.46) | EGFRNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL31034731 | 0.85 | EGFR (0.48) | EGFRNPC1RAB9AMAPTCSF1R | |
| SCHEMBL27345689 | 0.85 | EGFR (0.46) | EGFRCSF1RLPLLIPGDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |