Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27345888 | 0.91 | CREBBP (0.47) | CREBBPL3MBTL1RAB9AMAPTATM | |
| SCHEMBL30811602 | 0.83 | CREBBP (0.51) | CREBBPL3MBTL1RAB9AMAPTLMNA | |
| SCHEMBL27345913 | 0.83 | CREBBP (0.51) | CREBBPL3MBTL1RAB9AMAPTLMNA | |
| SCHEMBL27345904 | 0.80 | CREBBP (0.51) | CREBBPL3MBTL1RAB9AMAPTLMNA | |
| SCHEMBL30811556 | 0.80 | CREBBP (0.51) | CREBBPL3MBTL1RAB9AMAPTLMNA | |
| SCHEMBL30811567 | 0.77 | CREBBP (0.45) | CREBBPL3MBTL1RAB9AMAPTLMNA | |
| SCHEMBL27345920 | 0.77 | CREBBP (0.45) | CREBBPL3MBTL1RAB9AMAPTLMNA | |
| SCHEMBL28364247 | 0.76 | CYP3A4 (0.48) | L3MBTL1RAB9AMAPTATMNPSR1 | |
| SCHEMBL30811589 | 0.74 | CREBBP (0.50) | CREBBPL3MBTL1RAB9AMAPTLMNA | |
| SCHEMBL27345901 | 0.74 | CREBBP (0.50) | CREBBPL3MBTL1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |