Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27345913 | 1.00 | CREBBP (0.51) | CREBBPPKMALDH1A1HTTL3MBTL1 | |
| SCHEMBL9658234 | 0.86 | CREBBP (0.54) | CREBBPALDH1A1HTTL3MBTL1LMNA | |
| SCHEMBL27345904 | 0.83 | CREBBP (0.51) | CREBBPALDH1A1HTTL3MBTL1LMNA | |
| SCHEMBL30811556 | 0.83 | CREBBP (0.51) | CREBBPALDH1A1HTTL3MBTL1LMNA | |
| SCHEMBL29533055 | 0.83 | EPAS1 (0.52) | PKMALDH1A1HTTLMNAGAA | |
| SCHEMBL22826881 | 0.83 | EPAS1 (0.52) | PKMALDH1A1HTTLMNAGAA | |
| SCHEMBL27345897 | 0.83 | CREBBP (0.48) | CREBBPALDH1A1HTTL3MBTL1LMNA | |
| SCHEMBL22158823 | 0.81 | MAPT (0.53) | PKMALDH1A1L3MBTL1LMNAGAA | |
| Acetaldehyde SCHEMBL28708085 | 0.78 | EPAS1 (0.48) | PKMALDH1A1HTTL3MBTL1LMNA | |
| SCHEMBL30811589 | 0.77 | CREBBP (0.50) | CREBBPPKMALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543863-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | University Of Ottawa (CA) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |